Cancer became recently the leading cause of death in industrialized countries. Even though
standard treatments achieve significant effects in growth inhibition and tumor elimination …

Plants have had an essential role in the folklore of ancient cultures. In addition to the use as
food and spices, plants have also been utilized as medicines for over 5000 years. It is …

Aims This study aims at investigating the role of a neighbor long non-coding RNA (lncRNA)
of HDAC4 (LOC85009) in docetaxel (DTX) resistance of lung adenocarcinoma (LUAD) …

Taxol®, an antitumor drug with significant activity, is the first microtubule stabilizing agent
described in the literature. This short review of the mechanism of action of Taxol® …

Microtubule-stabilizing agents (MSAs) are efficacious chemotherapeutic drugs widely used
for the treatment of cancer. Despite the importance of MSAs for medical applications and …

The maturation of nanotechnology has revealed it to be a unique and distinct discipline
rather than a specialization within a larger field. Its textbook cannot afford to be a chemistry …

Plants, marine organisms, and microorganisms have evolved complex chemical defense
and signaling systems that are designed to protect them from predators and provide other …

Cancer is the second leading cause of death affecting nearly one in two people, and the
appearance of new cases is projected to rise by> 70% by 2030. To effectively combat the …

The mechanical properties of cells are important in tissue homeostasis and enable cell
growth, division, migration and the epithelial-mesenchymal transition. Mechanical properties …

Macrocyclic scaffolds are commonly found in bioactive natural products and pharmaceutical
molecules. So far, a large number of macrocyclic natural products have been isolated and …