A guide to the composition and functions of the extracellular matrix

NK Karamanos, AD Theocharis, Z Piperigkou… - The FEBS …, 2021 - Wiley Online Library
Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …

Wound healing: cellular mechanisms and pathological outcomes

HN Wilkinson, MJ Hardman - Open biology, 2020 - royalsocietypublishing.org
Wound healing is a complex, dynamic process supported by a myriad of cellular events that
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …

Defining the hallmarks of metastasis

DR Welch, DR Hurst - Cancer research, 2019 - AACR
Metastasis is the primary cause of cancer morbidity and mortality. The process involves a
complex interplay between intrinsic tumor cell properties as well as interactions between …

The extracellular matrix in tumor progression and metastasis

JA Eble, S Niland - Clinical & experimental metastasis, 2019 - Springer
The extracellular matrix (ECM) constitutes the scaffold of tissues and organs. It is a complex
network of extracellular proteins, proteoglycans and glycoproteins, which form …

The good and the bad collagens of fibrosis–their role in signaling and organ function

MA Karsdal, SH Nielsen, DJ Leeming… - Advanced drug delivery …, 2017 - Elsevier
Usually the dense extracellular structure in fibrotic tissues is described as extracellular
matrix (ECM) or simply as collagen. However, fibrosis is not just fibrosis, which is already …

Immunomodulatory role of the extracellular matrix within the liver disease microenvironment

CE McQuitty, R Williams, S Chokshi… - Frontiers in …, 2020 - frontiersin.org
Chronic liver disease when accompanied by underlying fibrosis, is characterized by an
accumulation of extracellular matrix (ECM) proteins and chronic inflammation. Although …

[HTML][HTML] The pre-Descemet's layer (Dua's layer, also known as the Dua-Fine layer and the pre-posterior limiting lamina layer): Discovery, characterisation, clinical and …

HS Dua, R Freitas, I Mohammed, DSJ Ting… - Progress in Retinal and …, 2023 - Elsevier
The pre-Descemet's layer/Dua's layer, also termed the Dua-Fine layer and the pre-posterior
limiting lamina layer, lies anterior to the Descemet's membrane in the cornea, is 10 μm …

The use of natural polymers in tissue engineering: a focus on electrospun extracellular matrix analogues

SA Sell, PS Wolfe, K Garg, JM McCool, IA Rodriguez… - Polymers, 2010 - mdpi.com
Natural polymers such as collagens, elastin, and fibrinogen make up much of the body's
native extracellular matrix (ECM). This ECM provides structure and mechanical integrity to …

Biological macromolecules-based nanoformulation in improving wound healing and bacterial biofilm-associated infection: A review

SS Garg, R Dubey, S Sharma, A Vyas… - International Journal of …, 2023 - Elsevier
A chronic wound is a serious complication associated with diabetes mellitus and is difficult to
heal due to high glucose levels, oxidative stress, and biofilm-associated microbial infection …

Electrospinning of collagen/biopolymers for regenerative medicine and cardiovascular tissue engineering

SA Sell, MJ McClure, K Garg, PS Wolfe… - Advanced drug delivery …, 2009 - Elsevier
The process of electrospinning has seen a resurgence of interest in the last few decades
which has led to a rapid increase in the amount of research devoted to its use in tissue …