S Zou, U Kumar - International journal of molecular sciences, 2018 - mdpi.com
The biological effects of cannabinoids, the major constituents of the ancient medicinal plant Cannabis sativa (marijuana) are mediated by two members of the G-protein coupled …
Cannabinoid receptors, endocannabinoids and the enzymes responsible for their biosynthesis and degradation constitute the endocannabinoid system. In recent decades …
Apart from having been used and misused for at least four millennia for, among others, recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …
D Haspula, MA Clark - International journal of molecular sciences, 2020 - mdpi.com
The identification of the human cannabinoid receptors and their roles in health and disease, has been one of the most significant biochemical and pharmacological advancements to …
The recent identification of cannabinoid receptors and their endogenous lipid ligands has triggered an exponential growth of studies exploring the endocannabinoid system and its …
There are at least two types of cannabinoid receptors, CB1 and CB2, both coupled to G- proteins. CB1 receptors are present in the central nervous system and CB1 and CB2 …
Most neurodegenerative disorders (NDD s) are characterized by cognitive impairment and other neurological defects. The definite cause of and pathways underlying the progression …
The anatomical distribution and density of cannabinoid receptors in the human brain was studied in one fetal (33weeks gestation), two neonatal (aged three to six months) and eight …
The term'endocannabinoid'—originally coined in the mid-1990s after the discovery of membrane receptors for the psychoactive principle in Cannabis, Δ9-tetrahydrocannabinol …