Stem cells are characterized by their ability to self-renew and differentiate into many different
cell types. Research has focused primarily on how these processes are regulated at a …

The transcriptional co‐activators YAP (or YAP1) and TAZ (or WWTR1) are frequently
activated during the growth and progression of many solid tumors, including lung, colorectal …

Despite recent advances, the poor outcomes in renal cell carcinoma (RCC) suggest novel
therapeutics are needed. Ferroptosis is a form of regulated cell death, which may have …

The early development of many organisms involves the folding of cell monolayers, but this
behaviour is difficult to reproduce in vitro; therefore, both mechanistic causes and effects of …

Conductive polymeric microneedle (MN) arrays as biointerface materials show promise for
the minimally invasive monitoring of analytes in biodevices and wearables. There is …

There is increasing evidence that both mechanical and biochemical signals play important
roles in development and disease. The development of complex organisms, in particular …

Mechanical signals are increasingly recognized as overarching regulators of cell behaviour,
controlling stemness, organoid biology, tissue development and regeneration. Moreover …

The penultimate effectors of the Hippo signaling pathways YAP and TAZ, are transcriptional
co-activator proteins that play key roles in many diverse biological processes, ranging from …

Mammalian organs comprise an extraordinary diversity of cell and tissue types.
Regenerative organs, such as the skin and gastrointestinal tract, use resident stem cells to …

Fibroblasts are the major cell population in the connective tissue of most organs, where they
are essential for their structural integrity. They are best known for their role in remodelling …