Tumour necrosis factor (TNF) is a classical, pleiotropic pro-inflammatory cytokine. It is also
the first 'adipokine'described to be produced from adipose tissue, regulated in obesity and …

Introduction Inflammation is a very important part of innate immunity and is regulated in
many steps. One such regulating step is the cytokine network, where tumor necrosis factor α …

Context Increased concentrations of inflammatory biomarkers predict antidepressant
nonresponse, and inflammatory cytokines can sabotage and circumvent the mechanisms of …

Cytokines are important mediators of various aspects of health and disease, including
appetite, glucose and lipid metabolism, insulin sensitivity, skeletal muscle hypertrophy and …

Survival of plasma cells is regulated by B-cell maturation antigen (BCMA), a membrane-
bound receptor activated by its agonist ligands BAFF and APRIL. Here we report that γ …

Breast cancer is the most frequently diagnosed cancer and the principal cause of mortality
by malignancy in women and represents a main problem for public health worldwide. Tumor …

Background–Preclinical and preliminary clinical data have suggested that tumor necrosis
factor-α (TNFα) may play a role in the evolution and progression of heart failure and that …

This article emphasizes significant recent advances regarding heat stress and its impact on
exercise performance, adaptations, fluid electrolyte imbalances, and pathophysiology …

Morphological changes observed in OA include cartilage erosion as well as a variable
degree of synovial inflammation. Current research attributes these changes to a complex …

The discovery of leptin has imparted great impetus to adipose tissue research by
demonstrating a more active role for the adipocyte in energy regulation. Besides leptin …