Glycoproteomics

I Bagdonaite, SA Malaker, DA Polasky… - Nature Reviews …, 2022 - nature.com
Protein glycosylation involves the co-translational or post-translational addition of glycans to
proteins and is a crucial protein modification in health and disease. The aim of …

Mass spectrometry-based techniques to elucidate the sugar code

M Grabarics, M Lettow, C Kirschbaum, K Greis… - Chemical …, 2021 - ACS Publications
Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …

Recommendations for reporting ion mobility Mass Spectrometry measurements

V Gabelica, AA Shvartsburg, C Afonso… - Mass spectrometry …, 2019 - Wiley Online Library
Here we present a guide to ion mobility mass spectrometry experiments, which covers both
linear and nonlinear methods: what is measured, how the measurements are done, and how …

A pragmatic guide to enrichment strategies for mass spectrometry–based glycoproteomics

NM Riley, CR Bertozzi, SJ Pitteri - Molecular & Cellular Proteomics, 2021 - ASBMB
Glycosylation is a prevalent, yet heterogeneous modification with a broad range of
implications in molecular biology. This heterogeneity precludes enrichment strategies that …

Analytical techniques for metabolomic studies: A review

K Segers, S Declerck, D Mangelings, YV Heyden… - Bioanalysis, 2019 - Taylor & Francis
Metabolomics is the comprehensive study of small-molecule metabolites. Obtaining a wide
coverage of the metabolome is challenging because of the broad range of physicochemical …

[PDF][PDF] Wang

Y Wang - Jia Z, Yi Q, Song L. The various components implied …, 2018 - tranassoc.com
Systems and methods are disclosed for communicating data in an integrated sensor network
having one or more nodes coupled to an optical sensor network and a radio frequency …

Aberrant glycosylation and cancer biomarker discovery: a promising and thorny journey

M Wang, J Zhu, DM Lubman, C Gao - Clinical Chemistry and …, 2019 - degruyter.com
Glycosylation is among the most important post-translational modifications for proteins and
is of intrinsic complex character compared with DNAs and naked proteins. Indeed, over 50 …

MS‐based glycomics and glycoproteomics methods enabling isomeric characterization

W Peng, CD Gutierrez Reyes, S Gautam… - Mass spectrometry …, 2023 - Wiley Online Library
Glycosylation is one of the most significant and abundant posttranslational modifications in
mammalian cells. It mediates a wide range of biofunctions, including cell adhesion, cell …

SLIM ultrahigh resolution ion mobility spectrometry separations of isotopologues and isotopomers reveal mobility shifts due to mass distribution changes

R Wojcik, G Nagy, IK Attah, IK Webb… - Analytical …, 2019 - ACS Publications
We report on separations of ion isotopologues and isotopomers using ultrahigh-resolution
traveling wave-based Structures for Lossless Ion Manipulations with serpentine ultralong …

In-depth site-specific analysis of N-glycoproteome in human cerebrospinal fluid and glycosylation landscape changes in Alzheimer's disease

Z Chen, Q Yu, Q Yu, J Johnson, R Shipman… - Molecular & Cellular …, 2021 - ASBMB
As the body fluid that directly interchanges with the extracellular fluid of the central nervous
system (CNS), cerebrospinal fluid (CSF) serves as a rich source for CNS-related disease …