Simple Summary Cancer-associated glycosylation changes are widely used as biomarkers
and strongly impact malignancy. However, the clinical significance of the deranged …

Background Radiotherapy is a conventional and effective local treatment for breast cancer.
However, residual or recurrent tumors appears frequently because of radioresistance. Novel …

Abstract Dehydrogenase/reductase member 2 (DHRS2) belongs to the short-chain
dehydrogenase/reductase (SDR) family. It was initially isolated from the nuclear extract of …

Abstract Objective Alpha-1, 3-mannosyltransferase (ALG3) is an oncoprotein associated
with multiple malignancies. We aimed to investigate the role and potential mechanisms of …

Drug-resistance is a major problem in acute myeloid leukemia (AML) chemotherapy.
Aberrant changes in specific N-glycans have been observed in leukemia multidrug …

Esophageal squamous cell carcinoma (ESCC) is highly prevailing in Asia and it is ranked in
the most aggressive squamous cell carcinomas. High-frequency loss of heterozygosity …

Colorectal cancer (CRC) is the third most common cancer in the world and distant
metastasis is the leading cause of death among CRC patients. However, the underlying …

Background: Here, we establish a prognostic signature based on glycosyltransferase-
related genes (GTRGs) for head and neck squamous cell carcinoma (HNSCC) patients …

Background CD8+ T cells are one of the central effector cells in the immune
microenvironment. CD8+ T cells play a vital role in the development and progression of lung …

Aberrant choline metabolism, characterized by an increase in total choline-containing
compounds, phosphocholine and phosphatidylcholine (PC), is a metabolic hallmark of …