New finds in the palaeoanthropological and genomic records have changed our view of the
origins of modern human ancestry. Here we review our current understanding of how the …

Nearly all genetic variants that influence disease risk have human-specific origins; however,
the systems they influence have ancient roots that often trace back to evolutionary events …

Population size history is essential for studying human evolution. However, ancient
population size history during the Pleistocene is notoriously difficult to unravel. In this study …

Advances in the sequencing and the analysis of the genomes of both modern and ancient
peoples have facilitated a number of breakthroughs in our understanding of human …

Anatomically modern humans interbred with Neanderthals and with a related archaic
population known as Denisovans. Genomes of several Neanderthals and one Denisovan …

If we restrict the use of Homo sapiens in the fossil record to specimens which share a
significant number of derived features in the skeleton with extant H. sapiens, the origin of our …

The spread of modern humans across the globe has led to genetic adaptations to diverse
local environments. Recent developments in genomic technologies, statistical analyses, and …

Despite broad agreement that Homo sapiens originated in Africa, considerable uncertainty
surrounds specific models of divergence and migration across the continent. Progress is …

While introgression from Neanderthals and Denisovans has been documented in modern
humans outside Africa, the contribution of archaic hominins to the genetic variation of …

Since anatomically modern humans dispersed Out of Africa, the evolutionary history of
Eurasian populations has been marked by introgressions from presently extinct hominins …