In recent years, Earth system sciences are urgently calling for innovation on improving
accuracy, enhancing model intelligence level, scaling up operation, and reducing costs in …

Abstract Systems biology has experienced dramatic growth in the number, size, and
complexity of computational models. To reproduce simulation results and reuse models …

Abstract The public Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) is an
innovative digital ecosystem that relates toxicological information for chemicals, genes …

Abstract The IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb; https://www.
guidetopharmacology. org) is an open-access, expert-curated, online database that …

Abstract The HUGO Gene Nomenclature Committee (HGNC) assigns unique symbols and
names to human genes. The HGNC database (www. genenames. org) currently contains …

Abstract The HUGO Gene Nomenclature Committee (HGNC) based at EMBL's European
Bioinformatics Institute (EMBL-EBI) assigns unique symbols and names to human genes …

Abstract The Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) harmonizes
cross-species heterogeneous data for chemical exposures and their biological …

To the Editor—The standardization, portability and reproducibility of analysis pipelines are
key issues within the bioinformatics community. Most bioinformatics pipelines are designed …

The FAIR Guiding Principles, published in 2016, aim to improve the findability, accessibility,
interoperability and reusability of digital research objects for both humans and machines …

We describe an update of MirGeneDB, the manually curated microRNA gene database.
Adhering to uniform and consistent criteria for microRNA annotation and nomenclature, we …