Noncoding RNAs in diagnosis and prognosis of graft‐versus‐host disease (GVHD)

MK Vajari, S Moradinasab, AM Yousefi… - Journal of Cellular …, 2022 - Wiley Online Library
Allogeneic hematopoietic stem cell transplantation (allo‐HSCT) is a functional therapy for a
plethora of hematologic malignancies and immune disorders. Graft‐versus‐host disease …

Innate immune activation by tissue injury and cell death in the setting of hematopoietic stem cell transplantation

TV Brennan, VR Rendell, Y Yang - Frontiers in immunology, 2015 - frontiersin.org
Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) with donor lymphocyte
infusion is the mainstay of treatment for many types of hematological malignancies, but the …

The upregulation of regenerative activity for Extracellular vesicles with melatonin modulation in chemically defined media

JY Kim, WK Rhim, J Woo, SG Cha, CG Park… - International Journal of …, 2022 - mdpi.com
Extracellular vesicles (EVs) derived from human mesenchymal stem cells (hMSCs) have
been widely known to have therapeutic effects by representing characteristics of the origin …

Serum miR-29a is upregulated in acute graft-versus-host disease and activates dendritic cells through TLR binding

P Ranganathan, A Ngankeu, NC Zitzer… - The Journal of …, 2017 - journals.aai.org
Acute graft-versus-host disease (aGVHD) continues to be a frequent and devastating
complication of allogeneic hematopoietic stem cell transplantation (HSCT), posing as a …

MicroRNA-155 modulates acute graft-versus-host disease by impacting T cell expansion, migration, and effector function

NC Zitzer, K Snyder, X Meng, PA Taylor… - The Journal of …, 2018 - journals.aai.org
Abstract MicroRNA-155 (miR-155) is a small noncoding RNA critical for the regulation of
inflammation as well as innate and adaptive immune responses. MiR-155 has been shown …

Differential MICRORNA expression levels in cutaneous acute graft-versus-host disease

S Atarod, J Norden, LA Bibby, A Janin… - Frontiers in …, 2018 - frontiersin.org
Allogeneic hematopoietic stem cell transplantation is a curative treatment for numerous
hematological malignancies. However, acute graft-versus-host disease (aGvHD) is a major …

Circulating miR-455-3p, miR-5787, and miR-548a-3p as potential noninvasive biomarkers in the diagnosis of acute graft-versus-host disease: a validation study

J Motaei, MA Kerachian, SA Mousavi… - Annals of …, 2021 - Springer
Currently, acute graft-versus-host disease (aGVHD) diagnosis is based on clinical features
and pathological findings. Until now, there is no non-invasive diagnostic test for aGVHD …

Genetic association of hematopoietic stem cell transplantation outcome beyond histocompatibility genes

R Gam, P Shah, RE Crossland, J Norden… - Frontiers in …, 2017 - frontiersin.org
The outcome of hematopoietic stem cell transplantation (HSCT) is controlled by genetic
factors among which the leukocyte antigen human leukocyte antigen (HLA) matching is most …

Tissue-specific expression patterns of microRNA during acute graft-versus-host disease in the rat

D Jalapothu, M Boieri, RE Crossland, P Shah… - Frontiers in …, 2016 - frontiersin.org
MicroRNAs (miRNA) have emerged as central regulators of diverse biological processes
and contribute to driving pathology in several diseases. Acute graft-versus-host disease …

MicroRNAs as biomarkers for graft-versus-host disease following allogeneic stem cell transplantation

C Tomuleasa, S Fuji, A Cucuianu, M Kapp… - Annals of …, 2015 - Springer
Allogeneic hematopoietic stem cell transplantation (HCT) is a well-established treatment for
many malignant and non-malignant hematological disorders. As frequent complication in up …