The physiological processes of cell growth, proliferation, differentiation, and apoptosis are
closely related to STAT3, and it has been demonstrated that aberrant STAT3 expression has …

Epithelial-to-mesenchymal transition (EMT) mechanism is responsible for metastasis of
tumor cells and their spread to various organs and tissues of body, providing undesirable …

Signal transducer and activator of transcription 3 (STAT3), a member of the STAT family,
discovered in the cytoplasm of almost all types of mammalian cells, plays a significant role in …

Anthocyanins are flavonoid compounds that are abundantly present in fruits and vegetables.
These compounds contribute to the color of these foods and offer various health benefits to …

The signal transducer and activator of transcription (STAT) 1 protein plays a key role in the
immune response against viruses and other pathogens by transducing, in the nucleus, the …

Oral squamous cell carcinoma (OSCC) usually originates from the precancerous lesions of
oral mucosa and accounts for approximately 90% of oral cancers. Current therapeutic …

The role of metabolites exchanged in the tumor microenvironment is largely thought of as
fuels to drive the increased biosynthetic and bioenergetic demands of growing tumors …

The body's normal immune response against any invading pathogen that causes infection in
the body results in inflammation. The sudden transformation in inflammation leads to the rise …

Hydrogen sulfide releasing agents (or H2S donors) have been recognized gasotransmitters
with potent cytoprotective and anticancer properties. However, the clinical application of …

Background: Signal transducers and activators of the transcription (STAT) family is
composed of seven structurally similar and highly conserved members, including STAT1 …