[HTML][HTML] Sex hormone fluctuation and increased female risk for depression and anxiety disorders: from clinical evidence to molecular mechanisms

M Kundakovic, D Rocks - Frontiers in neuroendocrinology, 2022 - Elsevier
Women are at twice the risk for anxiety and depression disorders as men are, although the
underlying biological factors and mechanisms are largely unknown. In this review, we …

Dentate gyrus circuits for encoding, retrieval and discrimination of episodic memories

T Hainmueller, M Bartos - Nature Reviews Neuroscience, 2020 - nature.com
The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …

[HTML][HTML] Neuronal types in the mouse amygdala and their transcriptional response to fear conditioning

H Hochgerner, S Singh, M Tibi, Z Lin… - Nature …, 2023 - nature.com
The amygdala is a brain region primarily associated with emotional response. The use of
genetic markers and single-cell transcriptomics can provide insights into behavior …

The role of adult hippocampal neurogenesis in brain health and disease

T Toda, SL Parylak, SB Linker, FH Gage - Molecular psychiatry, 2019 - nature.com
Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by a number
of environmental and cell-intrinsic factors to adapt to environmental changes. Accumulating …

Hippocampal neurogenesis confers stress resilience by inhibiting the ventral dentate gyrus

C Anacker, VM Luna, GS Stevens, A Millette, R Shores… - Nature, 2018 - nature.com
Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by
environmental influences, and functionally implicated in behavioural responses to stress …

[HTML][HTML] Astrocytic activation generates de novo neuronal potentiation and memory enhancement

A Adamsky, A Kol, T Kreisel, A Doron… - Cell, 2018 - cell.com
Astrocytes respond to neuronal activity and were shown to be necessary for plasticity and
memory. To test whether astrocytic activity is also sufficient to generate synaptic potentiation …

Adult hippocampal neurogenesis and cognitive flexibility—linking memory and mood

C Anacker, R Hen - Nature Reviews Neuroscience, 2017 - nature.com
Adult hippocampal neurogenesis has been implicated in cognitive processes, such as
pattern separation, and in the behavioural effects of stress and antidepressants. Young adult …

Encouraging an excitable brain state: mechanisms of brain repair in stroke

MT Joy, ST Carmichael - Nature Reviews Neuroscience, 2021 - nature.com
Stroke induces a plastic state in the brain. This period of enhanced plasticity leads to the
sprouting of new axons, the formation of new synapses and the remapping of sensory-motor …

Integration of optogenetics with complementary methodologies in systems neuroscience

CK Kim, A Adhikari, K Deisseroth - Nature Reviews Neuroscience, 2017 - nature.com
Modern optogenetics can be tuned to evoke activity that corresponds to naturally occurring
local or global activity in timing, magnitude or individual-cell patterning. This outcome has …

[HTML][HTML] Anxiety cells in a hippocampal-hypothalamic circuit

JC Jimenez, K Su, AR Goldberg, VM Luna, JS Biane… - Neuron, 2018 - cell.com
The hippocampus is traditionally thought to transmit contextual information to limbic
structures where it acquires valence. Using freely moving calcium imaging and …