Nanopore-based sensors have established themselves as a prominent tool for solution-
based, single-molecule analysis of the key building blocks of life, including nucleic acids …

Extracellular vesicles (EVs) are complex lipid membrane vehicles with variable expressions
of molecular cargo, composed of diverse subpopulations that participate in the intercellular …

Artificial intelligence applications have changed the landscape of computer design, driving a
search for hardware architecture that can efficiently process large amounts of data. Three …

Proteins can be the root cause of a disease, and they can be used to cure it. The need to
identify these critical actors was recognized early (1951) by Sanger; the first biopolymer …

Fast, cheap, and reliable DNA sequencing could be one of the most disruptive innovations
of this decade, as it will pave the way for personalized medicine. In pursuit of such …

Biotechnological innovations have vastly improved the capacity to perform large-scale
protein studies, while the methods we have for identifying and quantifying individual proteins …

Nanopore techniques offer a low-cost, label-free, and high-throughput platform that could be
used in single-molecule biosensing and in particular DNA sequencing. Since 2010 …

Established methods for characterizing proteins typically require physical or chemical
modification steps or cannot be used to examine individual molecules in solution. Ionic …

The human gut microbiota has become the subject of extensive research in recent years and
our knowledge of the resident species and their potential functional capacity is rapidly …

The discovery of genetic variation and the assembly of genome sequences are both
inextricably linked to advances in DNA-sequencing technology. Short-read massively …