Enzymatic noncovalent synthesis

H He, W Tan, J Guo, M Yi, AN Shy, B Xu - Chemical reviews, 2020 - ACS Publications
Enzymatic reactions and noncovalent (ie, supramolecular) interactions are two fundamental
nongenetic attributes of life. Enzymatic noncovalent synthesis (ENS) refers to a process …

Carrier-free nanomedicines for cancer treatment

LH Liu, XZ Zhang - Progress in Materials Science, 2022 - Elsevier
The last decade witnessed the great advances in the development of nanomedicines. As a
kind of attractive nanomedicine, carrier-free nanomedicines received extensive …

Precise subcellular organelle targeting for boosting endogenous‐stimuli‐mediated tumor therapy

W Zhen, S An, S Wang, W Hu, Y Li, X Jiang… - Advanced …, 2021 - Wiley Online Library
Though numerous external‐stimuli‐triggered tumor therapies, including phototherapy,
radiotherapy, and sonodynamic therapy have made great progress in cancer therapy, the …

Dynamic responsiveness of self‐assembling peptide‐based nano‐drug systems

Y Wang, J Zhan, J Huang, X Wang… - Interdisciplinary …, 2023 - Wiley Online Library
Dynamic‐responsive self‐assembly is the process of ordered supramolecular structure
formation or reversible decomposition from building blocks. This process is driven by non …

Targeted Enrichment of Enzyme‐Instructed Assemblies in Cancer Cell Lysosomes Turns Immunologically Cold Tumors Hot

S Ji, J Li, X Duan, J Zhang, Y Zhang… - Angewandte Chemie …, 2021 - Wiley Online Library
Lysosome‐relevant cell death induced by lysosomal membrane permeabilization (LMP) has
recently attracted increasing attention. However, nearly no studies show that currently …

Subcellular targeting strategies for protein and peptide delivery

H Su, G Rong, L Li, Y Cheng - Advanced Drug Delivery Reviews, 2024 - Elsevier
Cytosolic delivery of proteins and peptides provides opportunities for effective disease
treatment, as they can specifically modulate intracellular processes. However, most of …

In situ self-assembled peptide nanofibers for cancer theranostics

N Liu, L Zhu, Z Li, W Liu, M Sun, Z Zhou - Biomaterials Science, 2021 - pubs.rsc.org
Self-assembled nanofibers hold tremendous promise for cancer theranostics owing to their
in situ assembly, spatiotemporal responsiveness, and diverse bioactivity. Herein, this review …

Research on endoplasmic reticulum–targeting fluorescent probes and endoplasmic reticulum stress–mediated nanoanticancer strategies: a review

L Qiao, X Shao, S Gao, Z Ming, X Fu, Q Wei - Colloids and Surfaces B …, 2021 - Elsevier
Subcellular localization of organelles can achieve accurate drug delivery and maximize
drug efficacy. As the largest organelle in eukaryotic cells, the endoplasmic reticulum (ER) …

Pan-cancer analysis of FURIN as a potential prognostic and immunological biomarker

B Zhou, S Gao - Frontiers in molecular biosciences, 2021 - frontiersin.org
Background Furin is a calcium-dependent protease that processes various precursor
proteins through diverse secretory pathways. The deregulation of FURIN correlated with the …

Nanofibers in Organelles: From Structure Design to Biomedical Applications

JJ Hu, N Lin, Y Zhang, F Xia, X Lou - Angewandte Chemie, 2024 - Wiley Online Library
Nanofibers are one of the most important morphologies of molecular self‐assemblies, the
formation of which relies on the diverse intermolecular interactions of fibrous‐forming units …