Profiling of phytochemicals from aerial parts of Terminalia neotaliala using LC-ESI-MS2 and determination of antioxidant and enzyme inhibition activities

MN Shahzad, S Ahmad, MI Tousif, I Ahmad, H Rao… - PloS one, 2022 - journals.plos.org
Objectives Owing to extraordinary healing power, Terminalia species have been used in
traditional medicine systems to treat various diseases. Many folklore uses of Terminalia …

Chemical Characterization of Different Extracts of Justicia secunda Vahl and Determination of Their Anti-Oxidant, Anti-Enzymatic, Anti-Viral, and Cytotoxic Properties

Ł Świątek, E Sieniawska, KI Sinan, G Zengin… - Antioxidants, 2023 - mdpi.com
Justicia secunda Vahl. is a traditional medicinal plant in tropical regions, including West
Africa. The present study examined the chemical profiles and biological properties of J …

Cichorium intybus L. significantly alleviates cigarette smoke-induced acute lung injury by lowering NF-κB pathway activation and inflammatory mediators

N Hussain, N Ikram, L Hussain, AM Alqahtani… - Heliyon, 2023 - cell.com
Background Cigarette smoke (CS) is one of the primary causes of acute lung injury (ALI) via
provoking pulmonary inflammation and oxidative stress. Despite substantial studies, no …

Beyond Traditional Use of Alchemilla vulgaris: Genoprotective and Antitumor Activity In Vitro

S Jelača, Z Dajić-Stevanović, N Vuković, S Kolašinac… - Molecules, 2022 - mdpi.com
Alchemilla vulgaris L.(lady's mantle) was used for centuries in Europe and Balkan countries
for treatments of numerous conditions and diseases of the reproductive system, yet some of …

Biological activities of Hypericum spectabile extract optimized using artificial neural network combined with genetic algorithm application

A Gürgen, M Sevindik, T Krupodorova, I Uysal… - BMC biotechnology, 2024 - Springer
Optimizing extraction conditions can help maximize the efficiency and yield of the extraction
process while minimizing negative impacts on the environment and human health. For the …

Dandelion seeds as a new and valuable source of bioactive extracts obtained using the supercritical fluid extraction technique

S Milovanovic, A Grzegorczyk, Ł Świątek… - Sustainable Chemistry …, 2022 - Elsevier
The present study was intended to explore dandelion seeds as a new source of biologically
active constituents using an environmentally friendly extraction technique. The process …

Phytochemical Insights into Ficus sur Extracts and Their Biological Activity

E Sieniawska, Ł Świątek, KI Sinan, G Zengin… - Molecules, 2022 - mdpi.com
This study focused on the biological evaluation and chemical characterisation of Ficus sur
Forssk.(F. sur)(Family: Moraceae). The methanolic and aqueous extracts' phytochemical …

Bridging the Chemical Profiles and Biological Effects of Spathodea campanulata Extracts: A New Contribution on the Road from Natural Treasure to Pharmacy …

Ł Świątek, E Sieniawska, KI Sinan, G Zengin, AI Uba… - Molecules, 2022 - mdpi.com
Spathodea campanulata is an important medicinal plant with traditional uses in the tropical
zone. In the current work, we aimed to determine the chemical profiles and biological effects …

DIGEP‐Pred 2.0: A web application for predicting drug‐induced cell signaling and gene expression changes

SM Ivanov, AV Rudik, AA Lagunin… - Molecular …, 2024 - Wiley Online Library
The analysis of drug‐induced gene expression profiles (DIGEP) is widely used to estimate
the potential therapeutic and adverse drug effects as well as the molecular mechanisms of …

Chemical and Biological Studies of Endophytes Isolated from Marchantia polymorpha

M Stelmasiewicz, Ł Świątek, A Ludwiczuk - Molecules, 2023 - mdpi.com
Natural bioresources, predominantly plants, have always been regarded as the richest
source of drugs for diseases threatening humanity. Additionally, microorganism-originating …