Despite a marked decline in the incidence of gastric carcinoma in many industrialized
nations, cancer of the stomach remains the second most common cause of cancer-related …

In this article, we survey the major p53 (TP53) alterations identified in gastric carcinomas
and their precursors. These include p53 expression, mutations, and loss of heterozygosity …

This study was undertaken to determine the value of tumour microvessel density (MVD) and
the expression of p53 and vascular endothelial growth factor (VEGF) as prognostic markers …

PURPOSE The p53 gene encompasses 16 to 20 kb of DNA on the short arm of human
chromosome 17. It encodes for a 393-amino acid nuclear phosphoprotein involved in cell …

Background. Even after curative resection of an early gastric cancer, some patients die of a
recurrence. It is our view that patients with early gastric cancer who died of their disease had …

Background Despite gastric cancer being common, its prognosis has not been improved
significantly in recent years. Now, greater insight has been gained into the biological …

Background. Hematogenous metastasis occurs when cancer cells released from the primary
site enter blood vessels and are transported to distant organs, where they attach and …

Background: Although the TNM stage is the most important prognostic factor for gastric
cancer, there is a need for new prognostic and predictive factors, because the prognosis …

Gastric cancer is of major importance world-wide being the second most common cause of
cancer-related death in the world. According to Lauren's histological classification gastric …

Simple Summary The p53 family is a complex family of transcription factors with different
cellular functions that are involved in several physiological processes. A massive amount of …