Mesenchymal stem cell-based therapy for cardiovascular disease: progress and challenges

L Bagno, KE Hatzistergos, W Balkan, JM Hare - Molecular Therapy, 2018 - cell.com
Administration of mesenchymal stem cells (MSCs) to diseased hearts improves cardiac
function and reduces scar. These effects occur via stimulation of endogenous repair …

Use of mesenchymal stem cells for therapy of cardiac disease

V Karantalis, JM Hare - Circulation research, 2015 - Am Heart Assoc
Despite substantial clinical advances over the past 65 years, cardiovascular disease
remains the leading cause of death in America. The past 15 years has witnessed major …

Rebuilding the damaged heart: mesenchymal stem cells, cell-based therapy, and engineered heart tissue

S Golpanian, A Wolf, KE Hatzistergos… - Physiological …, 2016 - journals.physiology.org
Mesenchymal stem cells (MSCs) are broadly distributed cells that retain postnatal capacity
for self-renewal and multilineage differentiation. MSCs evade immune detection, secrete an …

Characteristics and therapeutic potential of human amnion-derived stem cells

QW Liu, QM Huang, HY Wu, GSL Zuo, HC Gu… - International journal of …, 2021 - mdpi.com
Stem cells including embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs)
and adult stem cells (ASCs) are able to repair/replace damaged or degenerative tissues and …

Human mesenchymal stem cell treatment of premature ovarian failure: new challenges and opportunities

YX Fu, J Ji, F Shan, J Li, R Hu - Stem Cell Research & Therapy, 2021 - Springer
Premature ovarian failure (POF) is one of the common disorders found in women leading to
1% female infertility. Clinical features of POF are hypoestrogenism or estrogen deficiency …

Human adult stem cells from diverse origins: an overview from multiparametric immunophenotyping to clinical applications

BR Sousa, RC Parreira, EA Fonseca… - Cytometry Part …, 2014 - Wiley Online Library
Stem cells are known for their capacity to self‐renew and differentiate into at least one
specialized cell type. Mesenchymal stem cells (MSCs) were isolated initially from bone …

Novel sources of fetal stem cells: where do they fit on the developmental continuum?

KI Pappa, NP Anagnou - Regenerative medicine, 2009 - Taylor & Francis
The recent isolation of fetal stem cells from several sources either at the early stages of
development or during the later trimesters of gestation, sharing similar growth kinetics and …

Human amniotic fluid mesenchymal stem cells from second‐and third‐trimester amniocentesis: differentiation potential, molecular signature, and proteome analysis

J Savickiene, G Treigyte, S Baronaite… - Stem cells …, 2015 - Wiley Online Library
Human amniotic fluid stem cells have become an attractive stem cell source for potential
applications in regenerative medicine and tissue engineering. The aim of this study was to …

Potential function of amniotic fluid in fetal development—novel insights by comparing the composition of human amniotic fluid with umbilical cord and maternal serum …

XL Tong, L Wang, TB Gao, YG Qin… - Journal of the Chinese …, 2009 - journals.lww.com
Background: Amniotic fluid (AF) is a dynamic and complex mixture. Up to now, little is known
about the physiological functions of AF in the process of fetal development. We suppose that …

Applications of amniotic membrane and fluid in stem cell biology and regenerative medicine

K Rennie, A Gruslin, M Hengstschläger… - Stem cells …, 2012 - Wiley Online Library
The amniotic membrane (AM) and amniotic fluid (AF) have a long history of use in surgical
and prenatal diagnostic applications, respectively. In addition, the discovery of cell …