Discoveries over the past decade portend a paradigm shift in molecular biology. Evidence
suggests that RNA is not only functional as a messenger between DNA and protein but also …

Type 2 diabetes (T2D) is a complex disease that is caused by a complex interplay between
genetic, epigenetic and environmental factors. While the major environmental factors, diet …

Background: MicroRNAs play essential roles in gene regulation. A substantial fraction of
microRNAs in tissues and body fluids is encapsulated in exosomes, thereby conferring …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the main cause
of dementia among the elderly worldwide. Despite intense efforts to develop drugs for …

Diabetes mellitus is the most common metabolic disorder worldwide and a major risk factor
for cardiovascular disease. MicroRNAs are negative regulators of gene expression that have …

Chronic inflammation is involved in the onset and development of many diseases, including
obesity, atherosclerosis, type 2 diabetes, osteoarthritis, autoimmune and degenerative …

Beta-cell dysfunction and impaired insulin production are hallmarks of diabetes 1, but
despite the growing diabetes epidemic, the molecular mechanisms underlying this disease …

Encapsulation of microRNAs in exosomes confers protection against degradation and a
vehicle for shuttling of microRNAs between cells and tissues, and cellular uptake by …

Background: Obesity is known to be a multifactorial disease. In its pathogenesis, different
factors such as chronic inflammation, oxidative stress, insulin resistance, genetic factors …

There is increasing evidence that miRNAs, which are enriched in nanovesicles called
exosomes, are important regulators of gene expression. When compared with normal …