Objective: The aim of the present review is to give an overview about the role, biosynthesis,
and characteristics of Podophyllotoxin (PTOX) as a potential antitumor agent with particular …

The aryltetralin-type lignan podophyllotoxin, the main agent present in the resin extracted
from the rhizomes of different podophyllum species, possesses important antineoplastic and …

Podophyllotoxin, a well-known naturally occurring aryltetralin lignan occurs in few plant
species that is used as a precursor for the chemical synthesis of the anticancer drugs like …

The natural lignan podophyllotoxin, a dimerized product of two phenylpropanoid moieties
which occurs in a few plant species, is a pharmacologically important compound for its …

Since ancient times (India, for 9000 years; South Mesopotamia, for 6000–7000 years;
Babylon and Egypt, for 5000 years) common flax (Linum usitatissimum L.) has been both …

Cancer is a collective name for a variety of diseases that can begin in virtually every organ
or body tissue as abnormal cells develop uncontrollably and ten million new cancer cases …

The aryltetralin lactone podophyllotoxin, which exhibits pronounced antineoplastic activity, is
used as the precursor of the following three clinical anticancer drugs: Etoposide™ …

Introduction–Podophyllotoxin, deoxypodophyllotoxin, demethylpodophyllotoxin and
podophyllotoxone are four therapeutically potent secondary metabolites. There is a dearth of …

The genus Linum consists of about 200 species of annual or perennial herbs or subshrubs.
Most of our knowledge of the chemical constituents of members of the genus is limited to far …

The impact of the two major components in flaxseed (α-linolenic acid and the lignan SDG)
on human health has been addressed in the preceding chapters. This chapter will focus on …