At least 20 million hepatitis E virus (HEV) infections occur annually, with> 3 million
symptomatic cases and∼ 60,000 fatalities. Hepatitis E is generally self-limiting, with a case …

Chemokines constitute a group of small, secreted proteins that regulate leukocyte migration
and contribute to their activation. Chemokines are crucial inflammatory mediators that play a …

Hepatotropic viruses naturally have narrow host and tissue tropisms, challenging the
development of robust experimental models. The advent of organoid technology provides a …

Interferons (IFNs) can serve as the first line of immune defense against viral infection. The
identification of IFN-λs 1, 2, 3 & 4 (termed as type III IFNs) has revealed that the antiviral …

Hepatitis E virus (HEV) is the most common cause of acute viral hepatitis throughout the
world. Most infections are acute but they can become chronic in immunocompromised …

The enterically transmitted hepatitis E virus (HEV) adopts a unique strategy to exit cells by
cloaking its capsid (encoded by the viral ORF2 gene) and circulating in the blood as “quasi …

Hepatitis E virus (HEV) infection, particularly HEV genotype 1 (HEV-1), can result in
fulminant hepatic failure and severe placental diseases, but mechanisms underlying …

Interferons (IFNs), which were discovered a half century ago, are a group of secreted
proteins that play key roles in innate immunity against viral infection. The major signaling …

Objective Hepatitis E virus (HEV), one of the most common agent of acute hepatitis
worldwide, is mainly transmitted enterically, via contaminated water for HEV genotypes 1 …

Hepatitis B virus (HBV) infection affects~ 350 million people and poses a major public health
problem worldwide. HBV is a major cause of cirrhosis and hepatocellular carcinoma. Fewer …