The current paradigm of inflammatory bowel diseases (IBD), both Crohn's disease (CD) and
ulcerative colitis (UC), involves the interaction between environmental factors in the …

The normal colonization of the mammalian intestine with commensal microbes is
hypothesized to drive the development of the humoral and cellular mucosal immune …

Intracellular bacteria are endowed with the capacity to survive and replicate inside
mononuclear phagocytes (MP) and, sometimes, within certain other host cells. MP are …

The lymphoid tissues associated with the intestine are exposed continuously to antigen and
are the largest part of the immune system. Many lymphocytes are found in organised tissues …

Tuberculosis is a chronic infectious disease which causes major health problems globally.
Acquired resistance is mediated by T lymphocytes and executed by activated macrophages …

T lymphocytes recognize specific ligands by clonally distributed T-cell receptors (TCR). In
humans and most animals, the vast majority of T cells express a TCR composed of an alpha …

Indirect evidence implicates γδ T cells in the cross-regulation of CD4 αβ T cell responses.
Adoptive transfer of small numbers of γδ T cells from ovalbumin (OVA)-tolerant mice …

The contribution of acute inflammation to sensory nerve regeneration was investigated in the
murine cornea using a model of corneal abrasion that removes the stratified epithelium and …

Flow cytofluorometric analyses of lymphocytes harvested from the mesenteric lymph node
(MLN), mucosal epithelium, and lamina propria of C57BL/6 mice demonstrate that …

Intraepithelial lymhocytes (IEL), particularly αβ TCR-bearing IEL (αβ-IEL), dramatically
increase in number after microbial colonization of formerly germ-free (ex-GF) mice (Umesaki …