Abstract c-kit is a classical proto-oncogene that encodes a receptor tyrosine kinase (RTK)
that responds to stem cell factor (SCF). C-KIT signaling is a critical regulator of cell …

Spermatogenesis, a study of germ cell development, is a long, orderly, and well‐defined
process occurring in seminiferous tubules of the testis. It is a temporal event whereby …

Aging men display reduced reproductive health; however, testis aging is poorly understood
at the molecular and genomic levels. Here, we utilized single-cell RNA-seq to profile over …

Embryonic germ cells as well as germline stem cells from neonatal mouse testis are
pluripotent and have differentiation potential similar to embryonic stem cells,, suggesting that …

Cytokines are regulatory proteins involved in haematopoiesis, immune cell development,
inflammation and immune responses. Several cytokines have direct effects on testicular cell …

Cytokinesis in somatic cells concludes with the formation of a midbody, which is abscised to
form individual daughter cells. In contrast, germ cell cytokinesis results in a permanent …

Follicle-stimulating hormone signaling is essential for the initiation and early stages of
spermatogenesis. Follicle-stimulating hormone receptor is exclusively expressed in Sertoli …

This paper is a review of the results of the authors obtained in a long-term experiment on fox
domestication. Debatable issues of dog evolution are discussed in light of these results. It is …

Increasing evidence indicates that microRNAs (miRNAs) may be critical players in
spermatogenesis. The miRNA expression profiles of THY1+-enriched undifferentiated …

Identification and isolation of spermatogonial stem cells (SSCs) are a prerequisite for
culture, genetic manipulation, and/or transplantation research. In this study, we established …