Applications of aptasensors in clinical diagnostics

P Hong, W Li, J Li - Sensors, 2012 - mdpi.com
Aptamers are artificial oligonucleotides (DNA or RNA) selected in vitro that bind a broad
range of targets with high affinity and specificity; a sensitive yet simple method to utilize …

[图书][B] Making and using antibodies: a practical handbook

GC Howard, MR Kaser - 2013 - books.google.com
Antibodies protect us from a wide range of infectious diseases and cancers and have
become an indispensable tool in science—both for conventional immune response research …

A highly sensitive and selective aptasensor based on graphene oxide fluorescence resonance energy transfer for the rapid determination of oncoprotein PDGF-BB

J Liang, R Wei, S He, Y Liu, L Guo, L Li - Analyst, 2013 - pubs.rsc.org
Oncoprotein platelet derived growth factor-BB (PDGF-BB) is one of the most critical growth
factors that regulates tumor growth and division. In this work, a highly sensitive and selective …

[HTML][HTML] Aptasensors in health, environment and food safety monitoring

A Sett, S Das, P Sharma, U Bora - Open Journal of Applied Biosensor, 2012 - scirp.org
Biosensors have been developed using various types of sensing elements like
biomacromolecules (viz. enzymes, antibodies, receptors, nucleic acids, etc.) organelles …

A highly sensitive and selective aptasensor based on fluorescence polarization for the rapid determination of oncoprotein vascular endothelial growth factor (VEGF)

SE Wang, Y Huang, K Hu, J Tian, S Zhao - Analytical Methods, 2014 - pubs.rsc.org
Vascular endothelial growth factor (VEGF) discrimination in blood is useful for the early
diagnosis, staging, and monitoring of cancers. However, effective and efficient methods are …

Aptamer-based sandwich assay for measurement of thymidine kinase 1 in serum of cancerous patients

M Nazari, SLM Gargari, A Sahebghadam Lotfi… - Biochemistry, 2019 - ACS Publications
Thymidine kinase 1 (TK1) is traditionally a serum biomarker that is elevated in the early
stages of malignancies. The diagnostic and prognostic role of TK1 for screening and …

Photophysical and Electrochemical Properties of Thienylnaphthalimide Dyes with Excellent Photostability

T Inari, M Yamano, A Hirano, K Sugawa… - The Journal of Physical …, 2014 - ACS Publications
The development of robust dyes is a highly important theme for any applications of dyes.
Here we present photophysical and electrochemical characterization of a set of robust dyes …

Ultrasensitive detection of potassium ions based on target induced DNA conformational switch enhanced fluorescence polarization

K Hu, Y Huang, S Zhao, J Tian, Q Wu, G Zhang, J Jiang - Analyst, 2012 - pubs.rsc.org
We have developed a simple, highly sensitive and selective fluorescence polarization assay
for the detection of potassium ions based on target induced DNA conformational switch from …

Selection and application of aptamers and intramers

M Avci-Adali - … Compounds: Prediction, Selection and Activity of …, 2016 - Springer
Aptamers are auspicious nucleic acid ligands for targeting different molecules, such as small
molecules, peptides, proteins, or even whole living cells. They are short single-stranded …

A highly sensitive fluorescence turn-on platform with silver nanoparticles aptasening for human platelet-derived growth factor-BB

X Wang, W Li, Z Li, H Li, D Xu - Talanta, 2015 - Elsevier
In this paper, we demonstrated a simple and highly sensitive fluorescence platform for
protein detection. Silver nanoparticles (AgNPs) worked as carriers and quenchers for FAM …