We here attempt to achieve an integrated understanding of the structure and dynamics of a
number of higher-order assemblies, including amyloids, various kinds of signalosomes, and …

▪ Abstract Tyrosine phosphorylation is one of the key covalent modifications that occurs in
multicellular organisms as a result of intercellular communication during embryogenesis and …

The vertebrate brain continues to produce new neurons throughout life,,,,,,,,,,,. In the rat
hippocampus, several thousand are produced each day, many of which die within weeks …

NMDA receptors are linked to intracellular cytoskeletal and signaling molecules via the PSD-
95 protein complex. We report a novel family of postsynaptic density (PSD) proteins, termed …

Nearly sixty years ago Fredrich Timm developed a histochemical technique that revealed a
rich reserve of free zinc in distinct regions of the brain. Subsequent electron microscopy …

Eph receptors constitute the largest family of tyrosine kinase receptors and, together with
their plasma-membrane-bound ephrin ligands, have many important functions during …

Virtually every aspect of cellular function within a metazoan organism, including proliferative
status, metabolism, gene expression, cytoskeletal organization, and indeed the cell's very …

The term 'vasculogenesis' refers to the earliest stages of vascular development, during
which vascular endothelial cell precursors undergo differentiation, expansion, and …

Summary Stromal interaction molecule-1 (STIM1) activates store-operated Ca 2+ entry
(SOCE) in response to diminished luminal Ca 2+ levels. Here, we present the atomic …

The interactions between Eph receptor tyrosine kinases and their ephrin ligands regulate
cell migration and axon pathfinding. The EphA receptors are generally thought to become …