Can anaesthetic and analgesic techniques affect cancer recurrence or metastasis?

A Heaney, DJ Buggy - British journal of anaesthesia, 2012 - academic.oup.com
Cancer is a leading cause of morbidity and mortality worldwide and the ratio of incidence is
increasing. Mortality usually results from recurrence or metastases. Surgical removal of the …

Perioperative anesthesia care and tumor progression

MW Sekandarzad, AAJ van Zundert, PB Lirk… - Anesthesia & …, 2017 - journals.lww.com
IMMUNE PATHOGENESIS The principal line of defense against cancer cell invasion and
metastasis is established via the host's innate and adaptive immune response. The key …

Prostate cancer cell malignancy via modulation of HIF-1α pathway with isoflurane and propofol alone and in combination

H Huang, LL Benzonana, H Zhao, HR Watts… - British journal of …, 2014 - nature.com
Background: Surgery is considered to be the first line treatment for solid tumours. Recently,
retrospective studies reported that general anaesthesia was associated with worse long …

Effect of anaesthetic technique on the natural killer cell anti-tumour activity of serum from women undergoing breast cancer surgery: a pilot study

A Buckley, S McQuaid, P Johnson… - British Journal of …, 2014 - academic.oup.com
Background Animal models and retrospective clinical data suggest that certain anaesthetic
techniques can attenuate immunosuppression and minimize metastasis after cancer …

Anesthetic technique and cancer recurrence in oncologic surgery: unraveling the puzzle

R Kim - Cancer and Metastasis Reviews, 2017 - Springer
Surgery/anesthetic technique-stimulated immunosuppression in the perioperative period
might cause an increase in cancer-related mortality. Whether anesthetic technique can affect …

Local anaesthetics: 10 essentials

P Lirk, S Picardi, MW Hollmann - European Journal of …, 2014 - journals.lww.com
This review seeks to address 10 essential questions regarding the clinical use of local
anaesthetics. Each local anaesthetic has distinctive physicochemical properties but with the …

Anaesthetic techniques for risk of malignant tumour recurrence

OS Cakmakkaya, K Kolodzie… - Cochrane Database …, 2014 - cochranelibrary.com
Background Surgery remains a mainstay of treatment for malignant tumours; however,
surgical manipulation leads to a significant systemic release of tumour cells. Whether these …

Implicating anaesthesia and the perioperative period in cancer recurrence and metastasis

JA Dubowitz, EK Sloan, BJ Riedel - Clinical & experimental metastasis, 2018 - Springer
Cancer, currently the leading cause of death in the population aged less than 85 years,
poses a significant global disease burden and is anticipated to continue to increase in …

Regional anaesthesia and analgesia: relationship to cancer recurrence and survival

T Tedore - BJA: British Journal of Anaesthesia, 2015 - academic.oup.com
Cancer treatment is associated with significant morbidity and mortality. Surgery is a mainstay
of treatment for many tumours, and anaesthetists care for cancer patients on a daily basis …

The effects of perioperative regional anesthesia and analgesia on cancer recurrence and survival after oncology surgery: a systematic review and meta-analysis

Y Sun, T Li, TJ Gan - Regional Anesthesia & Pain Medicine, 2015 - rapm.bmj.com
Background and Objectives Potentially, perioperative regional anesthesia and analgesia
(RA) could influence the outcomes of patients with cancer. The aim of this systematic review …