Evo-Devo of Urbilateria and its larval forms

EM De Robertis, N Tejeda-Muñoz - Developmental biology, 2022 - Elsevier
Developmental biology has contributed greatly to evolutionary biology in the past century.
With the discovery that vertebrates share Hox genes with Drosophila in 1984, it became …

Bone morphogenetic protein signaling: the pathway and its regulation

T Akiyama, LA Raftery, KA Wharton - Genetics, 2024 - academic.oup.com
In the mid-1960s, bone morphogenetic proteins (BMPs) were first identified in the extracts of
bone to have the remarkable ability to induce heterotopic bone. When the Drosophila gene …

[HTML][HTML] Natural size variation among embryos leads to the corresponding scaling in gene expression

A Leibovich, T Edri, SL Klein, SA Moody… - Developmental …, 2020 - Elsevier
Xenopus laevis frogs from laboratory stocks normally lay eggs exhibiting extensive size
variability. We find that these initial size differences subsequently affect the size of the …

Robust axis elongation by Nodal-dependent restriction of BMP signaling

A Schauer, K Pranjic-Ferscha, R Hauschild… - …, 2024 - journals.biologists.com
Embryogenesis results from the coordinated activities of different signaling pathways
controlling cell fate specification and morphogenesis. In vertebrate gastrulation, both Nodal …

Embryonic regeneration by relocalization of the Spemann organizer during twinning in Xenopus

Y Moriyama, EM De Robertis - Proceedings of the National …, 2018 - National Acad Sciences
The formation of identical twins from a single egg has fascinated developmental biologists
for a very long time. Previous work had shown that Xenopus blastulae bisected along the …

Deciphering the origin of developmental stability: The role of intracellular expression variability in evolutionary conservation

Y Uchida, M Tsutsumi, S Ichii, N Irie… - Evolution & …, 2024 - Wiley Online Library
Progress in evolutionary developmental biology (evo‐devo) has deepened our
understanding of how intrinsic properties of embryogenesis, along with natural selection and …

Dynamics of the secreted frizzled related protein Sizzled and potential implications for binding to bone morphogenetic protein-1 (BMP-1)

U Sharma, S Vadon-Le Goff, K Harlos, Y Zhao… - Scientific Reports, 2022 - nature.com
Sizzled (Szl) is both a secreted frizzled related protein (sFRP) and a naturally occurring
inhibitor of the zinc metalloproteinase bone morphogenetic protein-1 (BMP-1), a key …

Perspectives and applications of machine learning for evolutionary developmental biology

BC Feltes, BI Grisci, J de Faria Poloni, M Dorn - Molecular omics, 2018 - pubs.rsc.org
Evolutionary Developmental Biology (Evo-Devo) is an ever-expanding field that aims to
understand how development was modulated by the evolutionary process. In this …

[HTML][HTML] Transcriptome analysis of regeneration during Xenopus laevis experimental twinning

EA Sosa, Y Moriyama, Y Ding… - The International …, 2019 - ncbi.nlm.nih.gov
Animal embryos have the remarkable property of self-organization. Over 125 years ago,
Hans Driesch separated the two blastomeres of sea urchin embryos and obtained twins, in …

The genetic toolkit for tetrapod development and evolution

A Binda - 2023 - studenttheses.uu.nl
The developmental toolkit (genetic toolkit for development) is a group of highly conserved
genes that play crucial roles in developmental patterning and phenotypic evolution …