[HTML][HTML] Breakthroughs in hepatitis C research: from discovery to cure

MP Manns, B Maasoumy - Nature reviews Gastroenterology & …, 2022 - nature.com
In the 1970s, an unknown virus was suspected for documented cases of transfusion-
associated hepatitis, a phenomenon called non-A, non-B hepatitis. In 1989, the infectious …

Approved antiviral drugs over the past 50 years

E De Clercq, G Li - Clinical microbiology reviews, 2016 - Am Soc Microbiol
Since the first antiviral drug, idoxuridine, was approved in 1963, 90 antiviral drugs
categorized into 13 functional groups have been formally approved for the treatment of the …

EASL recommendations on treatment of hepatitis C: final update of the series☆

JM Pawlotsky, F Negro, A Aghemo, M Berenguer… - Journal of …, 2020 - Elsevier
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with
approximately 71 million chronically infected individuals worldwide. Clinical care for patients …

[PDF][PDF] Hepatitis C guidance 2019 update: American Association for the Study of Liver Diseases–Infectious Diseases Society of America recommendations for testing …

MG Ghany, TR Morgan… - …, 2020 - Wiley Online Library
HCV infection, risk-based screening failed to identify the majority of individuals with HCV
infection due to both clinician and patient barriers.(9-12) Analysis of the 2003-2010 National …

Oral direct-acting agent therapy for hepatitis C virus infection: a systematic review

O Falade-Nwulia, C Suarez-Cuervo… - Annals of internal …, 2017 - acpjournals.org
Background: Rapid improvements in hepatitis C virus (HCV) therapy have led to the
approval of multiple oral direct-acting antiviral (DAA) regimens by the US Food and Drug …

EASL recommendations on treatment of hepatitis C 2016

European Association for The Study of The Liver - Journal of hepatology, 2017 - Elsevier
Hepatitis C virus (HCV) infection is one of the main causes of chronic liver disease
worldwide [1]. The long-term impact of HCV infection is highly variable, ranging from minimal …

[HTML][HTML] Sofosbuvir, velpatasvir, and voxilaprevir for previously treated HCV infection

M Bourlière, SC Gordon, SL Flamm… - … England Journal of …, 2017 - Mass Medical Soc
Background Patients who are chronically infected with hepatitis C virus (HCV) and who do
not have a sustained virologic response after treatment with regimens containing direct …

[HTML][HTML] Glecaprevir–pibrentasvir for 8 or 12 weeks in HCV genotype 1 or 3 infection

S Zeuzem, GR Foster, S Wang… - … England Journal of …, 2018 - Mass Medical Soc
Background Glecaprevir and pibrentasvir are direct-acting antiviral agents with
pangenotypic activity and a high barrier to resistance. We evaluated the efficacy and safety …

[图书][B] Training course on the inpatient management of severe acute malnutrition: facilitator's guide

World Health Organization - 2021 - apps.who.int
The World Health Organization (WHO) Training course on the inpatient management of
severe acute malnutrition includes training modules, training guides, and supporting …

Hepatitis C virus infection

MP Manns, M Buti, ED Gane, JM Pawlotsky… - Nature reviews Disease …, 2017 - nature.com
Hepatitis C virus (HCV) is a hepatotropic RNA virus that causes progressive liver damage,
which might result in liver cirrhosis and hepatocellular carcinoma. Globally, between 64 and …