[HTML][HTML] Brain-derived neurotrophic factor signaling in depression and antidepressant action
E Castrén, LM Monteggia - Biological psychiatry, 2021 - Elsevier
Neurotrophic factors, particularly BDNF (brain-derived neurotrophic factor), have been
associated with depression and antidepressant drug action. A variety of preclinical and …
associated with depression and antidepressant drug action. A variety of preclinical and …
Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia
E Connell, G Le Gall, MG Pontifex, S Sami… - Molecular …, 2022 - Springer
A consequence of our progressively ageing global population is the increasing prevalence
of worldwide age-related cognitive decline and dementia. In the absence of effective …
of worldwide age-related cognitive decline and dementia. In the absence of effective …
The microbiota-gut-brain axis
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
Genetics factors in major depression disease
M Shadrina, EA Bondarenko, PA Slominsky - Frontiers in psychiatry, 2018 - frontiersin.org
Depressive disorders (DDs) are one of the most widespread forms of psychiatric pathology.
According to the World Health Organization, about 350 million people in the world are …
According to the World Health Organization, about 350 million people in the world are …
Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour
L Desbonnet, G Clarke, A Traplin, O O'Sullivan… - Brain, behavior, and …, 2015 - Elsevier
Background: There is growing appreciation for the importance of bacteria in shaping brain
development and behaviour. Adolescence and early adulthood are crucial developmental …
development and behaviour. Adolescence and early adulthood are crucial developmental …
The physiology of regulated BDNF release
T Brigadski, V Leßmann - Cell and Tissue Research, 2020 - Springer
The neurotrophic factor BDNF is an important regulator for the development of brain circuits,
for synaptic and neuronal network plasticity, as well as for neuroregeneration and …
for synaptic and neuronal network plasticity, as well as for neuroregeneration and …
A method for reproducible measurements of serum BDNF: comparison of the performance of six commercial assays
A Polacchini, G Metelli, R Francavilla, G Baj… - Scientific reports, 2015 - nature.com
Abstract Brain-Derived Neurotrophic Factor (BDNF) has attracted increasing interest as
potential biomarker to support the diagnosis or monitor the efficacy of therapies in brain …
potential biomarker to support the diagnosis or monitor the efficacy of therapies in brain …
BDNF Val66Met polymorphism, life stress and depression: A meta-analysis of gene-environment interaction
M Zhao, L Chen, J Yang, D Han, D Fang, X Qiu… - Journal of affective …, 2018 - Elsevier
Background Depression is thought to be multifactorial in etiology, including genetic and
environmental components. While a number of gene-environment interaction studies have …
environmental components. While a number of gene-environment interaction studies have …
Gene–environment interaction in major depression: focus on experience-dependent biological systems
N Lopizzo, L Bocchio Chiavetto, N Cattane… - Frontiers in …, 2015 - frontiersin.org
Major depressive disorder (MDD) is a multifactorial and polygenic disorder, where multiple
and partially overlapping sets of susceptibility genes interact each other and with the …
and partially overlapping sets of susceptibility genes interact each other and with the …
Integrating the monoamine, neurotrophin and cytokine hypotheses of depression—a central role for the serotonin transporter?
Monoamine, in particular serotonergic neurotransmission has long been recognized as an
important factor in the aetiology of depression. The serotonin transporter (SERT) is the …
important factor in the aetiology of depression. The serotonin transporter (SERT) is the …