Allostery: an illustrated definition for the 'second secret of life'

AW Fenton - Trends in biochemical sciences, 2008 - cell.com
Although allosteric regulation is the 'second secret of life', the molecular mechanisms that
give rise to allostery currently elude understanding. In my opinion, experimental progress is …

[PDF][PDF] The sodium pump

IM Glynn, SJD Karlish - Annual Review of Physiology, 1975 - scholar.archive.org
Th e recent startli ng growth of th e literature on th e sodium pump may make a review timely,
but it does not make the task of writing it easy. If the great mas s of work that has been done …

[图书][B] The regulation of cellular systems

R Heinrich, S Schuster - 2012 - books.google.com
There is no doubt that nowadays, biology benefits greatly from mathematics. In particular,
cellular biology is, besides population dynamics, a field where tech niques of mathematical …

Kinetic aspects of regulation of metabolic processes: The hysteretic enzyme concept

C Frieden - Journal of Biological Chemistry, 1970 - ASBMB
Hysteretic enzymes are defined as those enzymes which respond slowly (in terms of some
kinetic characteristic) to a rapid change in ligand, either substrate or modifier, concentration …

A simple method for derivation of rate equations for enzyme-catalyzed reactions under the rapid equilibrium assumption or combined assumptions of equilibrium and …

S Cha - Journal of biological chemistry, 1968 - Elsevier
A method is described by which rate equations for enzymic reactions under the equilibrium
assumptions may be derived by inspecting the reaction pathways without solving …

Mathematical theory of complex ligand-binding systems at equilibrium: some methods for parameter fitting

HA Feldman - Analytical biochemistry, 1972 - Elsevier
In this report, the equilibrium composition of a multicomponent crossreactive ligand-binding
system is characterized by solving the mass action equations. Several results in simulation …

Biological Feedback Control at the Molecular Level: Interaction between metabolite-modulated enzymes seems to be a major factor in metabolic regulation.

DE Atkinson - Science, 1965 - science.org
Daniel E. Atkinson tive effector may be used to indicate whether presenceof the effector
leads to increased or decreased affinity of the enzyme for substrates. Different regulatory …

[HTML][HTML] Stimulation of rat liver mitochondrial adenosine triphosphatase by anions.

RE Ebel, HA Lardy - Journal of Biological Chemistry, 1975 - Elsevier
The hydrolysis of MgATP by isolated rat liver mitochondrial ATPase (EC 3.6. 1.3) at pH 8.0
was stimulated by various anions. The rate of hydrolysis was increased from 18 to 170 …

Selectivity of the diacylglycerol kinase inhibitor 3-{2-(4-[bis-(4-fluorophenyl) methylene]-1-piperidinyl) ethyl}-2, 3-dihydro-2-thioxo-4 (1H) quinazolinone (R59949) …

Y Jiang, F Sakane, H Kanoh, JP Walsh - Biochemical pharmacology, 2000 - Elsevier
Diacylglycerol kinases (DGKs) attenuate diacylglycerol-induced protein kinase C activation
during stimulated phosphatidylinositol turnover. This reaction also initiates …

Isoenzymes of human alkaline phosphatase

WH Fishman, NK Ghosh - Advances in clinical chemistry, 1967 - Elsevier
Publisher Summary Isoenzyme refers to a biochemically distinct class of catalytically active
proteins with the same specificity of bond cleavage or alteration, which can occupy several …