The asymmetric hydrogenation of alkenes using transition metal catalysts continues to be a
growing field and a fundamental tool for organic synthetic chemists. In contrast to, for …

Asymmetric hydrogenation is one of the most important catalytic methods for the preparation
of optically active compounds. For a long time the range of olefins that could be …

Despite decades of research on homogeneous catalysts for asymmetric hydrogenations,
most of the alkenes studied have some functionality that can coordinate strongly to a metal …

The asymmetric hydrogenation of tetrasubstituted olefins provides direct access to very
useful biological molecules and intermediates. The development of the technology has been …

The catalytic enantioselective hydrogenation of prochiral olefins is a key reaction in
asymmetric synthesis. Its relevance applies to both industry and academia as an inherently …

Recently, the chemistry of chiral aromatic spiroketals has received much attention because
they are key substructures in biologically active natural products,[1] pharmaceuticals,[2] and …

Branch-Selective and Enantioselective Iridium-Catalyzed Alkene Hydroarylation via Anilide-Directed
C–H Oxidative Addition | Journal of the American Chemical Society ACS ACS Publications …

Chiral iridium catalysts have now been used in the asymmetric hydrogenation of largely
unfunctionalized olefins for a decade. Recently, they have also been applied to substrates …

Asymmetric hydrogenation of olefins is one of the most important reactions for the synthesis
of optically active compounds, especially in industry. Chiral iridium catalysts based on P, N …

Despite half a century's advance in the field of transition-metal-catalyzed asymmetric alkene
hydrogenation, the enantioselective hydrogenation of purely alkyl-substituted 1, 1 …