Epigenetic aging clocks have gained significant attention as a tool for predicting age-related
health conditions in clinical and research settings. They have enabled geroscientists to …

According to the Geroscience concept that organismal aging and age-associated diseases
share the same basic molecular mechanisms, the identification of biomarkers of age that can …

The prediction of chronological age from methylation-based biomarkers represents one of
the most promising applications in the field of forensic sciences. Age-prediction models …

Lipids are critical structural and functional architects of cellular homeostasis. Change in
systemic lipid profile is a clinical indicator of underlying metabolic pathologies, and …

Chronological age is the most important risk factor for the incidence of age-related diseases.
The pace of ageing determines the magnitude of that risk and can be expressed as …

Humans age at different rates and families with exceptional longevity provide an opportunity
to understand why some people age slower than others. Unique features exhibited by …

Epigenetic clocks are valuable tools for estimating both chronological and biological age by
assessing DNA methylation levels at specific CpG dinucleotides. While conventional …

Background Blood DNA methylation was associated with coronary heart disease (CHD) risk
in Caucasians. We investigated the association between DNA methylation in peripheral …

Down syndrome is the most frequently occurring genetic condition, with a substantial
escalation in risk associated with advanced maternal age. The syndrome is characterized by …

Background Cellular and molecular changes occur during aging, decreasing organ function.
The aging process was measured by several biomarkers, including DNA methylation …