In human in-vitro fertilization (IVF) embryos are routinely transferred to the uterus on day 2 or
day 3 of development. Resultant implantation and pregnancy rates are disappointingly low …

BACKGROUND The advances in the world of IVF during the last decades have been rapid
and impressive and culture media play a major role in this success. Until the 1980s fertility …

BACKGROUND: IVF is limited by low success rates and a confounding high multiple birth
rate contributing to prematurity, increased neonatal mortality and child handicap. These …

The regulation of 1-cell mouse embryo development in culture by amino acids was
investigated. When the 20 amino acids in Eagle's medium were present, blastocyst …

Along with the transition from maternal to embryonic genome control the mammalian
preimplantation embryo undergoes significant changes in its physiology during …

Considerable advances in media development for the culture of preimplantation mammalian
embryos have been made since mouse embryos were first cultured and successfully …

The role of amino acids, ethylenediaminetetraacetic acid (EDTA), transferrin, oxygen,
glucose, glutamine, taurine and ammonium in CFl mouse zygote development in culture …

The mammalian blastocyst exhibits an idiosyncratic metabolism, reflecting its unique
physiology and its ability to undergo implantation. Glucose is the primary nutrient of the …

The culture of murine oocytes and preimplantation embryos in vitro has been used
successfully for many years. However, this practice can result in cellular stress and reduced …

A metabonomic strategy, utilizing high-resolution 1H NMR spectroscopy in conjunction with
chemometric methods (discriminant analysis with orthogonal signal correction), has been …