Sodium homeostasis, a balance necessary for life

A Bernal, MA Zafra, MJ Simón, J Mahía - Nutrients, 2023 - mdpi.com
Body sodium (Na) levels must be maintained within a narrow range for the correct
functioning of the organism (Na homeostasis). Na disorders include not only elevated levels …

The enteric nervous system

KA Sharkey, GM Mawe - Physiological reviews, 2023 - journals.physiology.org
Of all the organ systems in the body, the gastrointestinal tract is the most complicated in
terms of the numbers of structures involved, each with different functions, and the numbers …

[HTML][HTML] Anatomy, abdomen and pelvis, small intestine

JT Collins, A Nguyen, M Badireddy - StatPearls [Internet], 2024 - ncbi.nlm.nih.gov
The small intestine is a crucial gastrointestinal segment involved in nutrient digestion and
absorption, various endocrine functions, and immune protection (see Image. Small …

Dietary L-Glu sensing by enteroendocrine cells adjusts food intake via modulating gut PYY/NPF secretion

J Gao, S Zhang, P Deng, Z Wu, B Lemaitre… - Nature …, 2024 - nature.com
Amino acid availability is monitored by animals to adapt to their nutritional environment.
Beyond gustatory receptors and systemic amino acid sensors, enteroendocrine cells (EECs) …

Mechanisms underlying food-triggered symptoms in disorders of gut-brain interactions

K Van den Houte, P Bercik, M Simren… - Official journal of the …, 2022 - journals.lww.com
There has been a dramatic increase in clinical studies examining the relationship between
disorders of gut-brain interactions and symptoms evoked by food ingestion in the upper and …

Alterations in cellular metabolic pathway and epithelial cell maturation induced by MYO5B defects are partially reversible by LPAR5 activation

M Momoh, S Rathan-Kumar… - American Journal …, 2024 - journals.physiology.org
Functional loss of the motor protein myosin Vb (MYO5B) induces various defects in intestinal
epithelial function and causes a congenital diarrheal disorder, namely, microvillus inclusion …

Postprandial consequences of lipid absorption in the onset of obesity: Role of intestinal CD36

LJ Lebrun, SM Milheiro, A Tavernier, I Niot - Biochimica et Biophysica Acta …, 2022 - Elsevier
Obesity has reached epidemic proportions and its incidence is still increasing. Obesity is an
excess of fat, which can have harmful consequences such as inflammation, insulin …

[HTML][HTML] Exploring the potential for an evolutionarily conserved role of the taste 1 receptor gene family in gut sensing mechanisms of fish

AR Angotzi, E Leal, S Puchol, JM Cerdá-Reverter… - Animal Nutrition, 2022 - Elsevier
In this study, we investigated the transcriptional spatio-temporal dynamics of the taste 1
receptor (T1R) gene family repertoire in seabream (Sparus aurata [sa]), during larval …

G protein‐coupled receptor‐mediated autophagy in health and disease

D Öz‐Arslan, ZA Durer, B Kan - British Journal of …, 2024 - Wiley Online Library
G protein‐coupled receptors (GPCRs) constitute the largest and most diverse superfamily of
mammalian transmembrane proteins. These receptors are involved in a wide range of …

Colonic Tuft Cells: The Less-Recognized Therapeutic Targets in Inflammatory Bowel Disease and Colorectal Cancer

F Sipos, G Műzes - International Journal of Molecular Sciences, 2024 - mdpi.com
Tuft cells are more than guardian chemosensory elements of the digestive tract. They
produce a variety of immunological effector molecules in response to stimulation; moreover …