Collagen-and hyaluronic acid-based hydrogels and their biomedical applications

Q Xu, JE Torres, M Hakim, PM Babiak, P Pal… - Materials Science and …, 2021 - Elsevier
Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …

Hyaluronan: molecular size‐dependent signaling and biological functions in inflammation and cancer

AG Tavianatou, I Caon, M Franchi… - The FEBS …, 2019 - Wiley Online Library
Hyaluronan (HA) is a linear nonsulfated glycosaminoglycan of the extracellular matrix that
plays a pivotal role in a variety of biological processes. High‐molecular weight HA exhibits …

High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat

X Tian, J Azpurua, C Hine, A Vaidya… - Nature, 2013 - nature.com
The naked mole rat (Heterocephalus glaber) displays exceptional longevity, with a
maximum lifespan exceeding 30 years,,. This is the longest reported lifespan for a rodent …

The content and size of hyaluronan in biological fluids and tissues

MK Cowman, HG Lee, KL Schwertfeger… - Frontiers in …, 2015 - frontiersin.org
Hyaluronan is a simple repeating disaccharide polymer, synthesized at the cell surface by
integral membrane synthases. The repeating sequence is perfectly homogeneous, and is …

Hyaluronan fragments: an information-rich system

R Stern, AA Asari, KN Sugahara - European journal of cell biology, 2006 - Elsevier
Hyaluronan is a straight chain, glycosaminoglycan polymer of the extracellular matrix
composed of repeating units of the disaccharide [-d-glucuronic acid-β1, 3-N-acetyl-d …

Hyaluronic acid electrospinning: Challenges, applications in wound dressings and new perspectives

KC Castro, MGN Campos, LHI Mei - International Journal of Biological …, 2021 - Elsevier
Hyaluronic acid (HA) has already been consolidated in the literature as an extremely
efficient biopolymer for biomedical applications. In addition to its biodegradability, HA also …

Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties

N Itano, T Sawai, M Yoshida, P Lenas… - Journal of Biological …, 1999 - ASBMB
Three mammalian hyaluronan synthase genes, HAS1, HAS2, and HAS3, have recently
been cloned. In this study, we characterized and compared the enzymatic properties of …

[PDF][PDF] Hyaluronan: preparation, structure, properties, and applications

L Lapcık Jr, L Lapcık, S De Smedt, J Demeester… - Chem …, 1998 - researchgate.net
Hyaluronan (HA, Figure 1), a high molecular weight biopolysaccharide, was discovered by
Meyer and Palmer in 1934 in the vitreous humor of cattle eyes. 1 HA is a member of a group …

Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages. The role of HA size and CD44.

CM McKee, MB Penno, M Cowman… - The Journal of …, 1996 - Am Soc Clin Investig
Hyaluronan (HA) is a glycosaminoglycan constituent of extracellular matrix. In its native form
HA exists as a high molecular weight polymer, but during inflammation lower molecular …

Photocrosslinkable polysaccharides for in situ hydrogel formation

KA Smeds, MW Grinstaff - … Research: An Official Journal of The …, 2001 - Wiley Online Library
In situ photopolymerization is an exciting new technique for tissue engineering. Two
photocrosslinkable polysaccharides composed of alginate and hyaluronan are described …