MicroRNAs (miRNAs) are small, non-coding RNAs that post-transcriptionally regulate gene
expression by binding to specific mRNA targets and promoting their degradation and/or …

Hepatocellular carcinoma (HCC) is associated with chronic inflammation and fibrosis arising
from different etiologies, including hepatitis B and C and alcoholic and nonalcoholic fatty …

Being the largest internal organ of the human body with the unique ability of self-
regeneration, the liver is involved in a wide variety of vital functions that require highly …

The liver is a central regulator of metabolism, and liver failure thus constitutes a major health
burden. Understanding how this complex organ develops during embryogenesis will yield …

Chemokines are a family of cytokines that orchestrate the migration and positioning of
immune cells within tissues and are critical for the function of the immune system. CCR2 …

MicroRNAs miR-122, miR-34a, miR-16 and miR-21 are commonly deregulated in liver
fibrosis and hepatocellular carcinoma. This study examined whether circulating levels of …

The mammalian liver is composed of repeating hexagonal units termed lobules. Spatially
resolved single-cell transcriptomics has revealed that about half of hepatocyte genes are …

Background & Aims microRNAs (miRNAs) are deregulated in non-alcoholic fatty liver
disease (NAFLD) and have been proposed as useful markers for the diagnosis and …

miR-122, a completely conserved liver-specific miRNA in vertebrates, is essential for the
maintenance of liver homeostasis. This 22 nucleotide RNA regulates diverse functions such …

Hepatocellular Carcinoma (HCC) is one of the most common malignant tumours in the
world. It is a heterogeneous group of a tumour that vary in risk factor and genetic and …