Obesity is a growing problem worldwide and is associated with a range of comorbidities,
including cognitive dysfunction. In this review we will address the evidence that obesity and …

Aging is the greatest risk factor for most diseases including cancer, cardiovascular disorders,
and neurodegenerative disease. There is emerging evidence that interventions that improve …

There is growing evidence that obesity has deleterious effects on the brain and cognitive
function in the elderly population. However, the specific mechanisms through which aging …

Population-based clinic-pathological studies have established that the most common
pathological substrate of dementia in community-dwelling elderly people is mixed …

With the world's population aging at a rapid rate, the prevalence of Alzheimer's disease (AD)
has significantly increased. These statistics are alarming given recent evidence that a third …

Obesity and consumption of a high-fat diet are known to increase the risk of Alzheimer's
disease (AD). Diets high in fat also increase disease neuropathology and/or cognitive …

In recent years there has been increased interest in whether vascular disease contributes to
Alzheimer's disease (AD). This review considers how modifiable risk factors such as …

Dementia prevalence increases with age and Alzheimer's disease (AD) accounts for up to
75% of cases. However, significant variability and overlap exists in the extent of amyloid-β …

Alzheimer's disease (AD) is a chronic, progressive and irreversible neurodegenerative
disease with clinical characteristics of memory loss, dementia and cognitive impairment …

The prevalence of dementia worldwide is growing at an alarming rate. A number of studies
and meta-analyses have provided evidence for increased risk of dementia in patients with …