DW Choi - Frontiers in neuroscience, 2020 - frontiersin.org
Interest in excitotoxicity expanded following its implication in the pathogenesis of ischemic brain injury in the 1980s, but waned subsequent to the failure of N-methyl-D-aspartate …
LM Plum, L Rink, H Haase - … journal of environmental research and public …, 2010 - mdpi.com
Compared to several other metal ions with similar chemical properties, zinc is relatively harmless. Only exposure to high doses has toxic effects, making acute zinc intoxication a …
A Lau, M Tymianski - Pflügers Archiv-European Journal of Physiology, 2010 - Springer
Glutamate excitotoxicity is a hypothesis that states excessive glutamate causes neuronal dysfunction and degeneration. As glutamate is a major excitatory neurotransmitter in the …
Polymer composites have established an excellent position among the technologically essential materials because of their wide range of applications. An enormous research …
MA Lovell, JD Robertson, WJ Teesdale… - Journal of the …, 1998 - Elsevier
Concentrations of copper (Cu), iron (Fe) and zinc (Zn) were measured in the rims and cores of senile plaques (SP) and in the neuropil of the amygdala of nine Alzheimer's disease (AD) …
The use of zinc in medicinal skin cream was mentioned in Egyptian papyri from 2000 BC (for example, the Smith Papyrus), and zinc has apparently been used fairly steadily throughout …
The past few years have witnessed dramatic progress on all frontiers of zinc neurobiology. The recent development of powerful tools, including zinc-sensitive fluorescent probes …
CJ Frederickson, SW Suh, D Silva, CJ Frederickson… - The Journal of …, 2000 - Elsevier
Zinc is essential to the structure and function of myriad proteins, including regulatory, structural and enzymatic. It is estimated that up to 1% of the human genome codes for zinc …
Zinc is present in presynaptic nerve terminals throughout the mammalian central nervous system and likely serves as an endogenous signaling substance. However, excessive …