The sleep-deprived human brain

AJ Krause, EB Simon, BA Mander, SM Greer… - Nature Reviews …, 2017 - nature.com
How does a lack of sleep affect our brains? In contrast to the benefits of sleep, frameworks
exploring the impact of sleep loss are relatively lacking. Importantly, the effects of sleep …

The role of sleep in emotional brain function

AN Goldstein, MP Walker - Annual review of clinical psychology, 2014 - annualreviews.org
Rapidly emerging evidence continues to describe an intimate and causal relationship
between sleep and emotional brain function. These findings are mirrored by long-standing …

Sleep deprivation, oxidative stress and inflammation

F Atrooz, S Salim - Advances in protein chemistry and structural biology, 2020 - Elsevier
Adequate sleep is essential for normal brain function, especially during early life
developmental stages as postnatal brain maturation occurs during the critical period of …

Chronic sleep deprivation altered the expression of circadian clock genes and aggravated Alzheimer's disease neuropathology

L Niu, F Zhang, X Xu, Y Yang, S Li, H Liu… - Brain …, 2022 - Wiley Online Library
Circadian disruption is prevalent in Alzheimer's disease (AD) and may contribute to
cognitive impairment, psychological symptoms, and neurodegeneration. This study aimed to …

One night of total sleep deprivation promotes a state of generalized hyperalgesia: a surrogate pain model to study the relationship of insomnia and pain

S Schuh-Hofer, R Wodarski, DB Pfau, O Caspani… - Pain®, 2013 - Elsevier
Sleep disturbances are highly prevalent in chronic pain patients. Understanding their
relationship has become an important research topic since poor sleep and pain are …

REM sleep instability–a new pathway for insomnia?

D Riemann, K Spiegelhalder, C Nissen… - …, 2012 - thieme-connect.com
Chronic insomnia afflicts approximately 10% of the adult population and is associated with
daytime impairments and an elevated risk for developing somatic and mental disorders …

Obstructive sleep apnea and cancer: epidemiologic links and theoretical biological constructs

D Gozal, R Farré, FJ Nieto - Sleep medicine reviews, 2016 - Elsevier
Sleep disorders have emerged as highly prevalent conditions in the last 50–75 y. Along with
improved understanding of such disorders, the realization that perturbations in sleep …

REM sleep: a biological and psychological paradox

JM Siegel - Sleep medicine reviews, 2011 - Elsevier
Sleep and rest can be satisfactorily explained as adaptive states 1, 2 whose core function is
energy conservation and behavioral regulation. In addition to these functions, certain …

Sleep loss and addiction

LA López-Muciño, F García-García… - Neuroscience & …, 2022 - Elsevier
Reducing sleep hours is a risk factor for developing cardiovascular, metabolic, and
psychiatric disorders. Furthermore, previous studies have shown that reduction in sleep time …

The prevalence and characteristics of REM sleep without atonia (RSWA) in patients taking antidepressants

K Lee, K Baron, R Soca, H Attarian - Journal of Clinical Sleep …, 2016 - jcsm.aasm.org
Study Objectives: The association of REM sleep without atonia (RSWA) as well as REM
sleep behavior disorder (RBD) with the intake of selective serotonin reuptake inhibitors …