Prediabetes and colorectal cancer (CRC) represent compelling health burdens responsible
for high mortality and morbidity rates, sharing several modifiable risk factors. It has been …

Obesity is a major global health issue with various metabolic complications. Both bariatric
surgery and dieting achieve weight loss and improve whole-body metabolism, but vary in …

Background & Aims Metabolic dysfunction-associated steatohepatitis (MASH) is one of the
most common liver diseases worldwide and is characterized by multi-tissue insulin …

Importance Prior findings from the Look AHEAD trial showed no significant reduction in the
risk of cardiovascular events by lifestyle-induced weight loss among individuals with type 2 …

OBJECTIVE We assessed the relationship of body weight time in target range (TTR) with
composite kidney outcome in people with overweight/obesity and type 2 diabetes mellitus …

Background: Microalgae like Phaeodactylum tricornutum (PT) contain the carotenoid,
fucoxanthin, which has been purported to promote fat loss, lower blood lipids, and improve …

Cold exposure induces heat loss and may thus threaten survival. In response, the organism
triggers compensatory responses, including activation of sympathetic tone and induction of …

Exercise has received considerable attention because of its importance not just in regulating
physiological function, but also in ameliorating multiple pathological processes. Among …

Background Weight loss and lifestyle intervention improve glucose tolerance delaying the
onset of type 2 diabetes (T2D), but individual responses are highly variable. Determining the …

Cardiometabolic diseases (CMDs), encompassing cardiovascular and metabolic
dysfunctions, characterized by insulin resistance, dyslipidemia, hepatic steatosis, and …