Organisms respond in multiple ways to microbial infections. Pathogen invasion tipically
triggers an inflammatory response where acute phase proteins (APP) have a key role …

Highlights•Biomarkers of severe dengue can potentially improve clinical dengue outcomes
and alleviate the healthcare burden in dengue-endemic settings.•Risk factors for severe …

Background Dengue infection can cause a wide spectrum of clinical outcomes. The severe
clinical manifestations occur sufficiently late in the disease course, during day 4–6 of illness …

Infection with dengue virus (DENV) can lead to a wide spectrum of clinical presentations,
ranging from asymptomatic infection to death. It is estimated that the disease manifests only …

Emerging mosquito-transmitted RNA viruses, such as Zika virus (ZIKV) and Chikungunya
represent human pathogens of an immense global health problem. In particular, ZIKV has …

Dengue is a major worldwide problem in tropical and subtropical areas; it is caused by four
different viral serotypes, and it can manifest as asymptomatic, mild, or severe. Many factors …

Dengue virus (DENV) infection is prevalent in tropical and subtropical regions of the world,
which is fatal if untreated symptomatically. Emergence of new genotype within serotypes led …

Abstract Background Dengue and West Nile viruses are highly cross-reactive and have
numerous parallels in geography, potential vector host (Aedes family of mosquitoes), and …

Background To investigate the association between interleukin-6 (IL-6)(rs1800795,
rs1800796, rs1800797, rs13306435, rs2069849) and interleukin-10 (IL-10)(rs1800871 …

Dengue fever is an acute viral infection transmitted by arthropods but may evolve to severe
clinical manifestations. Descriptions of the role of circulating immune modulators such as …