Micro total analysis systems. Latest advancements and trends

PS Dittrich, K Tachikawa, A Manz - Analytical chemistry, 2006 - ACS Publications
The area of micro total analysis systems (μTAS), also called “lab on a chip”, miniaturized or
microfluidic analysis systems, is a rapidly developing field. During the last several years, we …

Miniaturized PCR chips for nucleic acid amplification and analysis: latest advances and future trends

C Zhang, D Xing - Nucleic acids research, 2007 - academic.oup.com
The possibility of performing fast and small-volume nucleic acid amplification and analysis
on a single chip has attracted great interest. Devices based on this idea, referred to as micro …

An integrated rotary microfluidic system with DNA extraction, loop-mediated isothermal amplification, and lateral flow strip based detection for point-of-care pathogen …

BH Park, SJ Oh, JH Jung, G Choi, JH Seo… - Biosensors and …, 2017 - Elsevier
Abstract Point-of-care (POC) molecular diagnostics plays a pivotal role for the prevention
and treatment of infectious diseases. In spite of recent advancement in microfluidic based …

Advances in microfluidic PCR for point-of-care infectious disease diagnostics

S Park, Y Zhang, S Lin, TH Wang, S Yang - Biotechnology advances, 2011 - Elsevier
Global burdens from existing or emerging infectious diseases emphasize the need for point-
of-care (POC) diagnostics to enhance timely recognition and intervention. Molecular …

A fully integrated microfluidic genetic analysis system with sample-in–answer-out capability

CJ Easley, JM Karlinsey… - Proceedings of the …, 2006 - National Acad Sciences
We describe a microfluidic genetic analysis system that represents a previously undescribed
integrated microfluidic device capable of accepting whole blood as a crude biological …

Micropumps, microvalves, and micromixers within PCR microfluidic chips: Advances and trends

C Zhang, D Xing, Y Li - Biotechnology advances, 2007 - Elsevier
This review surveys the advances of microvalves, micropumps, and micromixers within PCR
microfluidic chips over the past ten years. First, the types of microvalves in PCR chips are …

Sample preparation

Y Chen, Z Guo, X Wang, C Qiu - Journal of Chromatography A, 2008 - Elsevier
A panorama of sample preparation methods has been composed from 481 references, with
a highlight of some promising methods fast developed during recent years and a somewhat …

Microfluidic platform towards point-of-care diagnostics in infectious diseases

W Su, X Gao, L Jiang, J Qin - Journal of Chromatography A, 2015 - Elsevier
Rapid and timely diagnosis of infectious diseases is a critical determinant of clinical
outcomes and general public health. For the detection of various pathogens, microfluidics …

An integrated, self-contained microfluidic cassette for isolation, amplification, and detection of nucleic acids

D Chen, M Mauk, X Qiu, C Liu, J Kim… - Biomedical …, 2010 - Springer
A self-contained, integrated, disposable, sample-to-answer, polycarbonate microfluidic
cassette for nucleic acid—based detection of pathogens at the point of care was designed …

An isothermal amplification reactor with an integrated isolation membrane for point-of-care detection of infectious diseases

C Liu, E Geva, M Mauk, X Qiu, WR Abrams, D Malamud… - Analyst, 2011 - pubs.rsc.org
A simple, point of care, inexpensive, disposable cassette for the detection of nucleic acids
extracted from pathogens was designed, constructed, and tested. The cassette utilizes a …