Long QT and short QT syndromes (LQTS and SQTS) are cardiac repolarization
abnormalities that are characterized by length perturbations of the QT interval as measured …

Hearing loss (HL) is the most prevalent sensory impairment in both childhood and
adulthood. 1, 2 According to the last update of the World Health Organization (WHO) …

Background—Data on the Jervell and Lange-Nielsen syndrome (J-LN), the long-QT
syndrome (LQTS) variant associated with deafness and caused by homozygous or …

Jervell and Lange-Nielsen syndrome (JLNS) is one of the most severe life-threatening
cardiac arrhythmias. Patients display delayed cardiac repolarization, associated high risk of …

Long QT syndrome (LQTS) refers to a group of “channelopathies”–disorders that affect
cardiac ion channels. The “family” concept of syndromes has been applied to the multiple …

OBJECTIVE. The goal was to clarify the audiologic aspects and causes of congenital
hearing loss in children who failed universal neonatal hearing screening. METHODS. A …

Background: Potassium channels (KCh) are the most diverse and ubiquitous class of ion
channels. KCh control membrane potential and contribute to nerve and cardiac action …

Ion channels are multisubunit proteins responsible for the generation and propagation of
action potentials in nerve, skeletal muscle, and heart as well as maintaining salt and water …

The auditory system is a fascinating sensory organ that overall, converts sound signals to
electrical signals of the nervous system. Initially, sound energy is converted to mechanical …

BACKGROUND. Mutations in five cardiac voltage‐gated ion channel genes, including
KCNQ1, HERG, SCN5A, KCNE1 and KCNE2, constitute the principal cause of inherited long …