The role of helper T cells in psoriasis
P Hu, M Wang, H Gao, A Zheng, J Li, D Mu… - Frontiers in …, 2021 - frontiersin.org
Psoriasis is a complex, chronic relapsing and inflammatory skin disorder with a prevalence
of approximately 2% in the general population worldwide. Psoriasis can be triggered by …
of approximately 2% in the general population worldwide. Psoriasis can be triggered by …
Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy
The tumour microenvironment is the primary location in which tumour cells and the host
immune system interact. Different immune cell subsets are recruited into the tumour …
immune system interact. Different immune cell subsets are recruited into the tumour …
Psoriasis
Psoriasis is a common, chronic papulosquamous skin disease occurring worldwide,
presenting at any age, and leading to a substantial burden for individuals and society. It is …
presenting at any age, and leading to a substantial burden for individuals and society. It is …
Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis
The immunopathogenesis of psoriasis, a common chronic inflammatory disease of the skin,
is incompletely understood. Here we demonstrate, using a combination of single cell and …
is incompletely understood. Here we demonstrate, using a combination of single cell and …
Regulatory T cells in embryo implantation and the immune response to pregnancy
SA Robertson, AS Care… - The Journal of clinical …, 2018 - Am Soc Clin Investig
At implantation, the embryo expresses paternally derived alloantigens and evokes
inflammation that can threaten reproductive success. To ensure a robust placenta and …
inflammation that can threaten reproductive success. To ensure a robust placenta and …
When worlds collide: Th17 and Treg cells in cancer and autoimmunity
HM Knochelmann, CJ Dwyer, SR Bailey… - Cellular & molecular …, 2018 - nature.com
The balance between Th17 cells and regulatory T cells (Tregs) has emerged as a prominent
factor in regulating autoimmunity and cancer. Th17 cells are vital for host defense against …
factor in regulating autoimmunity and cancer. Th17 cells are vital for host defense against …
[HTML][HTML] Necroptosis in the pathophysiology of disease
Over the past 15 years, elegant studies have demonstrated that in certain conditions,
programed cell death resembles necrosis and depends on a unique molecular pathway with …
programed cell death resembles necrosis and depends on a unique molecular pathway with …
Primary and acquired resistance to immune checkpoint inhibitors in metastatic melanoma
Immune checkpoint inhibitors have revolutionized the treatment of patients with advanced-
stage metastatic melanoma, as well as patients with many other solid cancers, yielding long …
stage metastatic melanoma, as well as patients with many other solid cancers, yielding long …
Alterations of the skin and gut microbiome in psoriasis and psoriatic arthritis
I Olejniczak-Staruch, M Ciążyńska… - International journal of …, 2021 - mdpi.com
Numerous scientific studies in recent years have shown significant skin and gut dysbiosis
among patients with psoriasis. A significant decrease in microbiome alpha-diversity …
among patients with psoriasis. A significant decrease in microbiome alpha-diversity …
Current concepts of psoriasis immunopathogenesis
Psoriasis is a recurrent, chronic, immune-mediated, systemic inflammatory disease of the
skin, joints, and other organic systems. After atopic dermatitis, chronic stationary psoriasis is …
skin, joints, and other organic systems. After atopic dermatitis, chronic stationary psoriasis is …