Tropomyosin (TM) is a major allergen in crustaceans, which often causes allergy and is fatal
to some consumers. Currently, the most effective treatment is to avoid ingesting TM …

Allergen immunotherapy (AIT) is the sole disease-modifying treatment for allergic rhinitis; it
prevents rhinitis from progressing to asthma and lowers medication use. AIT against mites …

Antibody development, delivery, and efficacy are influenced by antibody-antigen affinity
interactions, off-target interactions that reduce antibody bioavailability and …

Brucella is a typical facultative intracellular bacterium that can cause zoonotic infections. For
Brucella, it is difficult to eliminate with current medical treatment. Therefore, a multi-epitope …

Highlights•Summary of the basic principles of structure-based vaccine design.•Review of
recent advances (the years 2019–2021) in structure-based vaccine design.•Preview of …

Background With the increasing incidence of tuberculosis (TB) and the shortcomings of
existing TB vaccines to prevent TB in adults, new TB vaccines need to be developed to …

Background: Latent tuberculosis infection (LTBI) is the primary source of active tuberculosis
(ATB), but a preventive vaccine against LTBI is lacking. Methods: In this study, dominant …

Currently, there is limited knowledge about the immunological profiles of Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). We used computer-based …

Introduction The field of cancer therapy has undergone a major transformation in less than a
decade due to the introduction of checkpoint inhibitors, the advent of next generation …

Introduction The Bacillus Calmette-Guérin (BCG) vaccine, currently used against
tuberculosis (TB), exhibits inconsistent efficacy, highlighting the need for more potent TB …