Background The HIV viral protein R (Vpr) is a multifunction protein involved in the
pathophysiology of HIV‐1. Recent evidence has suggested that Vpr amino acid substitutions …

HIV-1 must replicate in cells that are equipped to defend themselves from infection through
intracellular innate immune systems. HIV-1 evades innate immune sensing through …

Although there have been many studies of gene variant association with different stages of
HIV/AIDS progression in United States and European cohorts, few gene-association studies …

Ung-type uracil-DNA glycosylases are frontline defenders of DNA sequence fidelity in
bacteria, plants and animals; Ungs also directly assist both innate and humoral immunity …

Persons in the early stages of HIV infection are the major drivers of new infections. These
individuals may also develop renal dysfunctions at this time. Nigeria, as other African …

Although there have been many studies of gene variant association with different stages of
HIV/AIDS progression in United States and European cohorts, few gene-association studies …

HIV-1 is a pandemic virus that has a continuing impact on human society. As treatments for
HIV-1 infection improve, new targets for viral inhibition have provided a means to reduce a …