Phase separation is a ubiquitous process and finds applications in a variety of biological, organic, and inorganic systems. Nature has evolved the ability to control phase separation to …
TJ Böddeker, KA Rosowski, D Berchtold… - Nature physics, 2022 - nature.com
Many membraneless organelles are liquid-like domains that form inside the active, viscoelastic environment of living cells through phase separation. To investigate the …
Biofilms are aggregates of bacterial cells surrounded by an extracellular matrix. Much progress has been made in studying biofilm growth on solid substrates; however, little is …
Liquid-liquid phase separation is a fundamental mechanism underlying subcellular organization. Motivated by the striking observation that optogenetically generated droplets in …
X Wei, J Zhou, Y Wang, F Meng - Physical Review Letters, 2020 - APS
We propose a continuum theory of the liquid-liquid phase separation in an elastic network, where phase-separated microscopic droplets rich in one fluid component can form as an …
In cells, phase-separated liquid condensates interact mechanically with surrounding elastic networks such as chromatin and cytoskeleton. By considering the trade-offs between elastic …
Biological cells use droplets to separate components and spatially control their interior. Experiments demonstrate that the complex, crowded cellular environment affects the droplet …
Phase separation of multicomponent liquid mixtures plays an integral part in many processes ranging from industry to cellular biology. In many cases the morphology of …
L Meng, S Mao, J Lin - … of the National Academy of Sciences, 2024 - National Acad Sciences
Many biomolecular condensates, including transcriptional condensates, are formed in elastic mediums. In this work, we study the nonequilibrium condensate dynamics in a …