Actin remodeling is at the heart of the response of cells to external or internal stimuli,
allowing a variety of membrane protrusions to form. Fifteen years ago, tunneling nanotubes …

Actin filament assembly typically occurs in association with cellular membranes. A large
number of proteins sit at the interface between actin networks and membranes, playing …

Tunnelling nanotubes (TNTs) connect distant cells and mediate cargo transfer for
intercellular communication in physiological and pathological contexts. How cells generate …

Sheet-like membrane protrusions at the leading edge, termed lamellipodia, drive 2D-cell
migration using active actin polymerization. Microspikes comprise actin-filament bundles …

Transporting epithelial cells like those that line the gut build large arrays of actin-supported
protrusions called microvilli, which extend from the apical surface into luminal spaces to …

Rho in filopodia (Rif), a member of the Rho family of small GTPases, induces filopodia
formation primarily on the dorsal surface of cells; however, its function remains largely …

Elevated expression and genetic aberration of IRTKS, also named as BAIAP2L1, have been
observed in many tumors, especially in tumor progression. however, the molecular and …

Lipid membranes are structural components of cell surfaces and intracellular organelles.
Alterations in lipid membrane shape are accompanied by numerous cellular functions …

Key points Mechanoelectrical transduction at auditory hair cells requires highly specialized
stereociliary bundles that project from their apical surface, forming a characteristic graded …

Filopodia are long finger-like actin-based structures that project out from the plasma
membrane as cells navigate and explore their extracellular environment. The initiation of …