'Multi-omics' data integration: applications in probiotics studies

ID Kwoji, OA Aiyegoro, M Okpeku, MA Adeleke - npj Science of Food, 2023 - nature.com
The concept of probiotics is witnessing increasing attention due to its benefits in influencing
the host microbiome and the modulation of host immunity through the strengthening of the …

Accounting gut microbiota as the mediator of beneficial effects of dietary (poly) phenols on skeletal muscle in aging

A Ticinesi, A Nouvenne, N Cerundolo, A Parise… - Nutrients, 2023 - mdpi.com
Sarcopenia, the age-related loss of muscle mass and function increasing the risk of disability
and adverse outcomes in older people, is substantially influenced by dietary habits. Several …

A gut aging clock using microbiome multi-view profiles is associated with health and frail risk

H Wang, Y Chen, L Feng, S Lu, J Zhu, J Zhao… - Gut …, 2024 - Taylor & Francis
Age-related changes in the microbiome have been reported in previous studies; however,
direct evidence for their association with frailty is lacking. Here, we introduce biological age …

Multi-omics analysis reveals neuroinflammation, activated glial signaling, and dysregulated synaptic signaling and metabolism in the hippocampus of aged mice

Y Lu, K Xu, D Lin, S Wang, R Fu, X Deng… - Frontiers in Aging …, 2022 - frontiersin.org
Aging is an intricate biological event that occurs in both vertebrates and invertebrates.
During the aging process, the brain, a vulnerable organ, undergoes structural and functional …

A genomic compendium of cultivated human gut fungi characterizes the gut mycobiome and its relevance to common diseases

Q Yan, S Li, Q Yan, X Huo, C Wang, X Wang, Y Sun… - Cell, 2024 - cell.com
The gut fungal community represents an essential element of human health, yet its
functional and metabolic potential remains insufficiently elucidated, largely due to the limited …

Does “all disease begin in the gut”? The gut-organ cross talk in the microbiome

PP Chaudhary, M Kaur, IA Myles - Applied Microbiology and …, 2024 - Springer
The human microbiome, a diverse ecosystem of microorganisms within the body, plays
pivotal roles in health and disease. This review explores site-specific microbiomes, their role …

Sex-based influential factors for dental caries in patients with schizophrenia

M Yang, J Xu, X Chen, L Liu, D Kong, Y Yang, W Chen… - BMC psychiatry, 2023 - Springer
Background Schizophrenia is a common mental disorder that seriously affects patients' daily
lives and brings heavy psychological and economic burdens to their families and society …

Oral and systemic health in Singapore: Revisiting the past to define the future

GG Nascimento, P Balan, S Alves‐Costa… - … Dentistry and Oral …, 2024 - Wiley Online Library
Objectives This study aimed to identify studies exploring oral and systemic conditions using
Singapore data. Methods Studies were searched using the databases PubMed, Embase …

[HTML][HTML] TRPA1 Influences Staphylococcus aureus Skin Infection in Mice and Associates with HIF-1a and MAPK Pathway Modulation

M Yadav, PP Chaudhary, G Ratley… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a major public
health burden. Emerging antibiotic resistance has heightened the need for new treatment …

The Aging Metabolite Database with Summary Statistics

D Milner, O Fiehn - arXiv preprint arXiv:2410.17417, 2024 - arxiv.org
Thousands of metabolomic papers are published each year, creating challenges for
scientists to combine results and yield conclusions that span across studies. Literature …