Dexmedetomidine as an adjuvant in peripheral nerve block

Z Chen, Z Liu, C Feng, Y Jin, X Zhao - Drug Design, Development …, 2023 - Taylor & Francis
Peripheral nerve block technology is important to balanced anesthesia technology. It can
effectively reduce opioid usage. It is the key to enhance clinical rehabilitation as an …

[HTML][HTML] Adjuvant drugs for peripheral nerve blocks: The role of NMDA antagonists, neostigmine, epinephrine, and sodium bicarbonate

AN Edinoff, JS Fitz-Gerald, KAA Holland… - … and Pain Medicine, 2021 - ncbi.nlm.nih.gov
The potential for misuse, overdose, and chronic use has led researchers to look for other
methods to decrease opioid consumption in patients with acute and chronic pain states. The …

[HTML][HTML] Pain control after mastectomy in transgender patients: ultrasound-guided pectoral nerve block II versus conventional intercostal nerve block: a randomized …

F Rokhtabnak, S Sayad, M Izadi… - … and Pain Medicine, 2021 - ncbi.nlm.nih.gov
Background Mastectomy is sometimes performed in transgender patients, which may
damage the regional nerves such as the pectoral and intercostobrachial nerves, leading to …

[HTML][HTML] Comparison of dexmedetomidine and dexamethasone as adjuvants to ultra-sound guided interscalene block in arthroscopic shoulder surgery: a double …

R Margulis, J Francis, B Tischenkel… - … and Pain Medicine, 2021 - ncbi.nlm.nih.gov
Background Interscalene block is one of the popular methods for decreasing pain and
analgesic consumption after shoulder arthroscopic surgeries. Objectives The objective is to …

[HTML][HTML] Comparison of intercostal nerve block with ropivacaine and ropivacaine-dexmedetomidine for postoperative pain control in patients undergoing thoracotomy …

K Mahmoudi, M Rashidi, F Soltani… - … and Pain Medicine, 2021 - ncbi.nlm.nih.gov
Background Thoracotomy is one of the most painful surgeries, and failure to alleviate
patients' pain can have dangerous consequences. Objectives This study aimed to evaluate …

[HTML][HTML] Adding dexmedetomidine to bupivacaine in ultrasound-guided thoracic paravertebral block for pain management after upper abdominal surgery: a double …

M Alimian, F Imani, P Rahimzadeh… - … and pain medicine, 2021 - ncbi.nlm.nih.gov
Background Paravertebral blocks are one of the possible postoperative pain management
modalities after laparotomy. Adjuvants to local anesthetics, including alpha agonists, have …

[HTML][HTML] Supraclavicular vs. infraclavicular brachial plexus nerve blocks: clinical, pharmacological, and anatomical considerations

AD Kaye, V Allampalli, P Fisher, AJ Kaye… - … and Pain Medicine, 2021 - ncbi.nlm.nih.gov
Peripheral nerve blocks (PNB) have become standard of care for enhanced recovery
pathways after surgery. For brachial plexus delivery of anesthesia, both supraclavicular (SC) …

[HTML][HTML] Biased, Bitopic, Opioid–Adrenergic Tethered Compounds May Improve Specificity, Lower Dosage and Enhance Agonist or Antagonist Function with Reduced …

R Root-Bernstein - Pharmaceuticals, 2022 - mdpi.com
This paper proposes the design of combination opioid–adrenergic tethered compounds to
enhance efficacy and specificity, lower dosage, increase duration of activity, decrease side …

[HTML][HTML] Ilioinguinal and iliohypogastric nerve block for acute and chronic pain relief after caesarean section: A randomized controlled trial

L Elahwal, S Elrahwan, AA Elbadry - Anesthesiology and Pain …, 2022 - ncbi.nlm.nih.gov
Background There is an increasing cesarean section (CS) rate in Egypt. Multiple methods
are used to manage pain after CS. Objectives This study aimed to assess the effect of …

Adjunctive dexamethasone palmitate use for intercostal nerve block after video-assisted thoracoscopic surgery: A prospective, randomized control trial

H Hui, H Miao, F Qiu, Y Lin, H Li, Y Zhang, B Jiang - Heliyon, 2023 - cell.com
Objectives The efficacy of dexamethasone palmitate in extending durations of local
anesthetic blocks is uncertain. In a randomized, double-blind study of patients undergoing …