Alkaloid molecules can act, depending on a type of amine functionality present in alkalods,
as either hydrogenacceptor or hydrogen-donor for hydrogen bonding that is critically …

Maytansine is a pharmacologically active 19-membered ansamacrolide derived from
various medicinal plants and microorganisms. Among the most studied pharmacological …

Leishmaniasis is a parasitic disease and categorised as a neglected tropical disease (NTD).
Each year, between 70, 0000 and 1 million new cases are believed to occur. There are …

The use of indigenous or remote popular knowledge to identify new drugs against diseases
or infections is a well-known approach in medicine. The inhabitants of coastal regions are …

Covering: 2012. Previous review: Nat. Prod. Rep. 2012, 29, 1334. This review covers the
isolation, structural determination, synthesis and chemical and microbiological …

Pyridine and pyridine-fused ring systems are ubiquitous in medicinal research and
demonstrate such diverse pharmacological benefits as anticonvulsant therapies, treatment …

Ortho-alkylated and ortho-acylated pyridines have been conveniently synthesized from
pyridine N-oxides and alkynes under visible-light-mediation in a metal-free manner. The …

Background: Chagas disease (American Trypanosomiasis) is classified by the World Health
Organization (WHO) as one of the seventeen neglected tropical diseases (NTD), affecting …

Pyridine (py) is one of the important heterocyclic compounds and an internal part of several
natural products. There are various medicines containing pyridine ring system being …

Eleven densely functionalized new dihydro-β-agarofuran sesquiterpenoid derivatives,
named maytenoids A–K (1–11), as well as one known analog, were isolated and …